Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized
by autoantibodies production and immune complex deposition with systemic clinical …

The involvement of the interleukin (IL)-17 axis in many inflammatory and autoimmune
diseases is now well established, and this has led to the development of successful targeted …

Systemic lupus erythematosus (SLE) is a complicated autoimmune disease of multifactorial
pathoaetiology. One of the most serious manifestations is lupus nephritis. The pathogenesis …

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by immune
cell abnormalities which lead to the production of autoantibodies and the deposition of …

Purpose The purpose of this review is to discuss the significance of IL-17 in SLE and the
potential of IL-17-targeted therapy. Background Systemic lupus erythematosus (SLE) is an …

Despite the success of targeted therapies in managing immune-mediated inflammatory
diseases (IMIDs) such as RA, IBDs, MS and psoriasis, unmet needs for such approach in …

The emerging role of interleukin (IL)-17 as a hallmark proinflammatory cytokine of the
adaptive immune system, produced primarily by a new T helper cell subset termed 'Th17' …

Objective The interleukin 17 (IL-17) cytokine family is involved in a number of chronic
inflammatory diseases. In spite of contradictory findings and a lack of causality in clinical …

Abstract The interleukin-17 (IL-17) family comprises six members (IL-17A–17F), and
recently, all of its related receptors have been discovered. IL-17 was first discovered …

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a broad
spectrum of clinical manifestations. The proposed pathophysiological hypotheses of SLE are …