In recent years, transdermal drug delivery based on microneedles (MNs) technology has
received extensive attention, which offers a safer and painless alternative to hypodermic …

Microneedle arrays (MNA) are considered as one of the most promising resources to
achieve systemic effects by transdermal delivery of drugs. They are designed as a minimally …

Introduction: Transdermal drug delivery offers a number of advantages for the patient, not
only due to its non-invasive and convenient nature, but also due to factors such as …

The outermost layer of skin, the epidermis, has developed formidable physical and
immunological barrier properties that prevent infiltration of deleterious chemicals and …

Microneedles (MNs) are micron-scaled needles measuring 100 to 1000 μm that were
initially explored for delivery of therapeutic agents across the skin. Considering the success …

The stratum corneum (SC) represents a significant barrier to the delivery of gene therapy
formulations. In order to realise the potential of therapeutic cutaneous gene transfer, delivery …

The most widely used methods for transdermal administration of the drugs are hypodermic
needles, topical creams, and transdermal patches. The effect of most of the therapeutic …

Transdermal delivery of drugs offers an interesting alternative for the administration of
molecules that present certain troubles when delivered by the oral route. It can produce …

With the limitations of oral drug delivery and the pain and needle phobias associated with
traditional injections, drug delivery research has focused on the transdermal delivery route …

Transdermal drug delivery (TDD) has many advantages, the main one being the ability to
maintain the prolonged release of drugs to attain optimal blood concentrations …