During a meal, multiple gastrointestinal sites are stimulated by ingested nutrients and their
digestion products, initiating local gastrointestinal actions and producing a variety of …

Individual meals are products of a complex interaction of signals related to both short-term
and long-term availability of energy stores. In addition to maintaining the metabolic demands …

The vagal afferent pathway is the major neural pathway by which information about ingested
nutrients reaches the CNS and influences both GI function and feeding behavior. Vagal …

The landmark discovery by Bayliss and Starling in 1902 of the first hormone, secretin,
emerged from earlier observations that a response (pancreatic secretion) following a …

Gastrointestinal tract (GIT) and nervous system, both central (CNS) and enteric (ENS), are
involved in two-way extrinsic communication by parasympathetic and sympathetic nerves …

Although the gastrointestinal (GI) tract possesses intrinsic neural plexuses that allow a
significant degree of autonomy over GI functions, the central nervous system (CNS) provides …

Over the past few years, scientific interest in the gut–brain axis (ie, the bidirectional
communication system between the gastrointestinal tract and the brain) has exploded …

To assess nutrient sensitivity in a population of gastric load-sensitive vagal afferents, their
neurophysiological activity was examined in anesthetized rats with inflated pyloric cuffs after …

During the past 30 yr, investigating the physiology of eating behaviors has generated a truly
vast literature. This is fueled in part by a dramatic increase in obesity and its comorbidities …

Nutrient sensing plays an important role in ensuring that appropriate digestive or hormonal
responses are elicited following the ingestion of fuel substrates. Mechanisms of nutrient …