The dorsal vagal complex in the medulla oblongata is the hub of the central nervous system
network that produces vagal cephalic-phase reflexes. The preganglionic motor neurons …

A foregone conclusion is that central neural and endocrine control of gastrointestinal
functions is based on a complex array of interconnecting brain structures, neurochemical …

The role of gastrointestinal hormones in the regulation of appetite is reviewed. The
gastrointestinal tract is the largest endocrine organ in the body. Gut hormones function to …

The response of the gastrointestinal tract (GIT) to ingestion of food is a complex and closely
controlled process, which allows optimization of propulsion, digestion, absorption of …

The arrival of nutrients in the gastrointestinal tract suppresses intake. To specify the neural
pathways and receptor locations of this feedback, we examined the effects of intraduodenal …

Background The enteric nervous system (ENS) of the gastrointestinal tract has traditionally
been viewed as a system of ganglia that operates largely independently of the brain and …

It is now axiomatic that neurons in the hypothalamic arcuate nucleus have a primary role in
responding to changes in circulating levels of leptin and transmitting signals to downstream …

The wall of the gut responds to an impressive array of signals originating in the lumen,
including nutrient and non-nutrient chemicals, mechanical factors, and micro-organisms …

Peripheral mechanisms in appetite regulation include the motor functions of the stomach,
such as the rate of emptying and accommodation, which convey symptoms of satiation to the …

Communication between the gut and brain is critical for homeostasis, but how this
communication is represented in the dynamics of feeding circuits is unknown. Here we …