Werner's syndrome (WS) or progeria adultorum is a heritable autosomal recessive disease
in which the aging process is accelerated, just after puberty. It is caused by mutations in the …

Background Werner's syndrome is a progeroid syndrome caused by mutations at the WRN
helicase locus. Some features of this disorder are also present in laminopathies caused by …

Werner syndrome (WS) is an autosomal recessive disorder characterized by the premature
occurrence of many age-related features. Previously, the WS gene (WRN) was mapped …

Werner syndrome (WS) is a rare autosomal recessive disorder characterized by systemic
accelerated aging. It is caused by pathogenic variants of the WRN gene that encodes a …

Patients with Werner's syndrome have the appearance of premature ageing. Neurological
complications are usually regarded as uncommon. The neurological manifestations in three …

Werner syndrome (WS) is an adult onset segmental progeroid syndrome caused by
mutations in the WRN gene. The WRN gene encodes a 180 kDa nuclear protein that …

The gene encoding the mouse Werner syndrome gene (WRN) was cloned using reverse
transcription-polymerase chain reaction and sequenced. The 5058-bp cDNA encoded a …

An unusual case of Werner's syndrome with myelodysplastic syndrome (MDS) in a 63-year-
old male is reported. He was transferred to our hospital for evaluation of pancytopenia in …

Epidemiology Patients with WS have been identified worldwide, with the largest number in
Japan (1017). Estimates of the frequency or prevalence of WS, obtained from casecounting …

Werner syndrome (WS) is an autosomal recessive genetic disease characterized by many
age-related features. The gene responsible for WS (WRN) has been isolated and contains a …