Recent work has shown that meningeal lymphatic vessels (mLVs), mainly in the dorsal part
of the skull, are involved in the clearance of cerebrospinal fluid (CSF), but the precise route …

Ageing is a major risk factor for many neurological pathologies, but its mechanisms remain
unclear. Unlike other tissues, the parenchyma of the central nervous system (CNS) lacks …

Cerebrospinal fluid (CSF) in the subarachnoid space around the brain has long been known
to drain through the lymphatics to cervical lymph nodes,,,,,,,,,,,,,,,–, but the connections and …

Cerebrospinal fluid (CSF) has been commonly accepted to drain through arachnoid
projections from the subarachnoid space to the dural venous sinuses. However, a lymphatic …

The central nervous system (CNS) is considered an organ devoid of lymphatic vasculature.
Yet, part of the cerebrospinal fluid (CSF) drains into the cervical lymph nodes (LNs). The …

Meningeal lymphatic vessels have been described in animal studies, but limited comparable
data is available in human studies. Here we show dural lymphatic structures along the dural …

Neuroinflammatory diseases, such as multiple sclerosis, are characterized by invasion of the
brain by autoreactive T cells. The mechanism for how T cells acquire their encephalitogenic …

The many interactions between the nervous and the immune systems, which are active in
both physiological and pathological states, have recently become more clearly delineated …

One of the characteristics of the central nervous system is the lack of a classical lymphatic
drainage system. Although it is now accepted that the central nervous system undergoes …

Cranial lymphatic vessels (LVs) are involved in the transport of fluids, macromolecules and
central nervous system (CNS) immune responses. Little information about spinal LVs is …