The never-ending public health issue of adulterants in abused drugs
FP Busardò, S Pichini, R Pacifici… - Journal of Analytical …, 2016 - academic.oup.com
Dear Sir, Illicit drugs have always contained other substances in addition to the claimed
active ingredient, leading to potential health threats or even to premature death. Adulterants …
active ingredient, leading to potential health threats or even to premature death. Adulterants …
Clinical issues associated with urine testing of substances of abuse
KD Eskridge, SK Guthrie - Pharmacotherapy: The Journal of …, 1997 - Wiley Online Library
Several factors may affect the validity and outcome of urine testing for abused drugs such as
amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, opiates …
amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, opiates …
Determination of chromate adulteration of human urine by automated colorimetric and capillary ion electrophoretic analyses
KE Ferslew, AN Nicolaides… - Journal of analytical …, 2003 - academic.oup.com
Various chemicals can be added to urine specimens collected for drug analysis to
abnormally elevate ionic concentrations and/or interfere with either immunoassay urine drug …
abnormally elevate ionic concentrations and/or interfere with either immunoassay urine drug …
A rapid non‐target screening method for determining prohibited substances in human urine using liquid chromatography/high‐resolution tandem mass spectrometry
B Han, H Min, M Jeon, B Kang… - Drug testing and analysis, 2019 - Wiley Online Library
Target analysis using liquid chromatography–tandem mass spectrometry is applied for
rapidly detecting various prohibited doping substances. Frequent modification is required as …
rapidly detecting various prohibited doping substances. Frequent modification is required as …
[引用][C] Defining limit of detection and limit of quantitation as applied to drug of abuse testing: striving for a consensus
GM Lawson - Clinical chemistry, 1994 - academic.oup.com
The minimum concentrations of an analyte that can be reliably detected or measured in an
analytical proce-dure are important performance characteristics of the assay. Over the years …
analytical proce-dure are important performance characteristics of the assay. Over the years …
False-positive postmortem EMIT drugs-of-abuse assay due to lactate dehydrogenase and lactate in urine
G Sloop, M Hall, GT Simmons… - Journal of analytical …, 1995 - academic.oup.com
Three cases of multiple false-positive drug tests are described. Postmortem urine specimens
were screened using the enzyme-multiplied immunoassay technique. All patients had …
were screened using the enzyme-multiplied immunoassay technique. All patients had …
Screening for drugs of abuse (II): Cannabinoids, lysergic acid diethylamide, buprenorphine, methadone, barbiturates, benzodiazepines and other drugs
D Simpson, RA Braithwaite, DR Jarvie… - Annals of clinical …, 1997 - journals.sagepub.com
Screening urine samples for drugs of abuse is important for the confirmation of drug misuse
and for the clinical management of drug misusers. Laboratories providing this service …
and for the clinical management of drug misusers. Laboratories providing this service …
The effect of glutaraldehyde adulteration of urine specimens on Syva EMIT II drugs-of-abuse assays
S George, RA Braithwaite - Journal of analytical toxicology, 1996 - academic.oup.com
The effect of glutaraldehyde (the active component of “UrinAid”) on Syva EMIT II drugs-of-
abuse screening assays was studied. It was found that, dependent on the assay involved …
abuse screening assays was studied. It was found that, dependent on the assay involved …
Drug Testing in the Workplace—Are Methods Legally Defensible?: A Survey of Experts, Arbitrators, and Testing Laboratories
DW Hoyt, RE Finnigan, T Nee, TF Shults, TJ Butler - JAMA, 1987 - jamanetwork.com
Urinalysis results are increasingly being used by employers to detect use of prohibited
substances in the workplace. Actions taken on the basis of positive urinalysis results can …
substances in the workplace. Actions taken on the basis of positive urinalysis results can …
The characterization of human urine for specimen validity determination in workplace drug testing: a review
JD Cook, YH Caplan, CP LoDico… - Journal of Analytical …, 2000 - academic.oup.com
One challenge facing the laboratory forensic toxicologist today is verifying the validity of the
random urine specimen submitted for workplace drugs of abuse analysis. Determining …
random urine specimen submitted for workplace drugs of abuse analysis. Determining …