Participation of urokinase-type plasminogen activator receptor in the clearance of fibrin from the lung
N Hattori, TH Sisson, Y Xu, TJ Desai… - American Journal of …, 1999 - journals.physiology.org
In vitro studies have demonstrated that the binding of urokinase-type plasminogen activator
(uPA) to its cell surface receptor (uPAR) greatly accelerates plasminogen activation …
(uPA) to its cell surface receptor (uPAR) greatly accelerates plasminogen activation …
[HTML][HTML] Urokinase induces expression of its own receptor in Beas2B lung epithelial cells
S Shetty, S Idell - Journal of Biological Chemistry, 2001 - ASBMB
Interaction between the urokinase-type plasminogen activator (uPA) and its receptor (uPAR)
localizes cellular proteolysis and promotes cellular proliferation and migration. The …
localizes cellular proteolysis and promotes cellular proliferation and migration. The …
Urokinase induces its own expression in Beas2B lung epithelial cells
S Shetty, UR Pendurthi, PKS Halady… - … of Physiology-Lung …, 2002 - journals.physiology.org
The urokinase-type plasminogen activator (uPA) interacts with its receptor (uPAR) to
promote local proteolysis as well as cellular proliferation and migration. These functions …
promote local proteolysis as well as cellular proliferation and migration. These functions …
Differential expression of the urokinase receptor in fibroblasts from normal and fibrotic human lungs.
S Shetty, A Kumar, AR Johnson, S Pueblitz… - American journal of …, 1996 - atsjournals.org
Binding of urokinase-type plasminogen activator (uPA) to a specific receptor (uPAR) on
human lung fibroblasts enables it to regulate cellular proteolysis and remodeling of the …
human lung fibroblasts enables it to regulate cellular proteolysis and remodeling of the …
Alveolar macrophage urokinase receptors localize enzyme activity to the cell surface
HA Chapman, P Bertozzi, LZ Sailor… - American Journal of …, 1990 - journals.physiology.org
Human alveolar macrophages are known to synthesize urokinase (uPA) and a specific
plasminogen activator inhibitor, PAI-2. In this study we have identified a uPA receptor …
plasminogen activator inhibitor, PAI-2. In this study we have identified a uPA receptor …
Urokinase mediates fibrinolysis in the pulmonary microvasculature
K Bdeir, JC Murciano, J Tomaszewski… - Blood, The Journal …, 2000 - ashpublications.org
The role of urokinase-type plasminogen activator (uPA) and its receptor (uPAR) in
fibrinolysis remains unsettled. The contribution of uPA may depend on the vascular location …
fibrinolysis remains unsettled. The contribution of uPA may depend on the vascular location …
[HTML][HTML] Induction of plasminogen activator inhibitor-1 by urokinase in lung epithelial cells
The plasminogen/plasmin system, urokinase-type plasminogen activator (uPA), its receptor
(uPAR), and its inhibitor (PAI-1), influence extracellular proteolysis and cell migration in lung …
(uPAR), and its inhibitor (PAI-1), influence extracellular proteolysis and cell migration in lung …
A urokinase receptor mRNA binding protein from rabbit lung fibroblasts and mesothelial cells
S Shetty, S Idell - … Journal of Physiology-Lung Cellular and …, 1998 - journals.physiology.org
The urokinase receptor (uPAR) influences several biological functions relevant to lung injury
and repair, including proteolysis, cell migration, and adhesion. In malignant mesothelioma …
and repair, including proteolysis, cell migration, and adhesion. In malignant mesothelioma …
Urokinase-type plasminogen activator induces tyrosine phosphorylation of a 78-kDa protein in H-157 cells
GJ Bhat, JJ Gunaje, S Idell - American Journal of …, 1999 - journals.physiology.org
Studies from our laboratory have shown that exposure of human lung epithelial cells to
urokinase plasminogen activator (uPA) induces their proliferation. This effect of uPA is likely …
urokinase plasminogen activator (uPA) induces their proliferation. This effect of uPA is likely …
[HTML][HTML] Characterisation of urokinase plasminogen activator receptor variants in human airway and peripheral cells
CE Stewart, I Sayers - BMC molecular biology, 2009 - Springer
Background Expression of the urokinase plasminogen activator receptor (UPAR) has been
shown to have clinical relevance in various cancers. We have recently identified UPAR as …
shown to have clinical relevance in various cancers. We have recently identified UPAR as …