This narrative review summarizes the current knowledge of the genetic and epigenetic
contributions to the development of fibromyalgia (FM). Although there is no single gene that …

Fibromyalgia is a common idiopathic pain condition often resulting in increased morbidity
and disability in patients. The lack of peripheral abnormalities in this disease has led …

Abstract Fibromyalgia (FM) affects 1% to 5% of the population, and approximately 90% of
the affected individuals are women. FM patients experience impaired quality of life and the …

This article reviews current findings regarding the pathophysiologic abnormalities that
contribute to the enhanced pain responses of individuals with fibromyalgia as well as the …

Although debate on the concept of fibromyalgia (FM) has been vigorous ever since the
classification criteria were first published, FM is now better understood and has become …

Our understanding of fibromyalgia (FM) has made significant advances over the past
decade. The current concept views FM as the result of central nervous system malfunction …

Fibromyalgia syndrome (FMS), a condition characterized by chronic widespread pain and
tenderness, is a complex condition considered to represent a paradigm of centralized pain …

In the past decade, we have made tremendous progress in our understanding of
fibromyalgia, which is now recognized as one of many'central'pain syndromes that are …

This article presents evidence that fibromyalgia patients have alterations in CNS anatomy,
physiology, and chemistry that potentially contribute to the symptoms experienced by these …

Animal models of disease states are valuable tools for development of new treatments, as
well as examining underlying mechanisms. An animal model of disease should mimic the …