OBJECTIVE: The aim of this study was to determine the effects of repeated courses of
prenatal corticosteroid therapy versus placebo on death or neurologic impairment among …

Some very preterm neonates admitted to the neonatal intensive care unit show circulatory
and respiratory problems that improve after administration of steroids. It is unclear whether …

Objective To determine the associations between age at first postnatal corticosteroids (PNS)
exposure and risk for severe bronchopulmonary dysplasia (BPD) and neurodevelopmental …

Objectives To compare brain volumes in adolescents who were born extremely preterm (<
28 weeks gestation) who had received postnatal dexamethasone, and to determine if there …

Objectives Antenatal corticosteroids (ACS) decrease neonatal mortality and morbidity
among preterm neonates, yet there has been concern regarding their long-term safety. We …

Infants at higher risk of bronchopulmonary dysplasia had increased rates of survival free of
cerebral palsy after postnatal corticosteroid treatment in a previous metaregression of data …

Inflammation is a key contributor to the pathogenesis of bronchopulmonary dysplasia (BPD)
in preterm infants, and cortisol plays a central role in controlling inflammation. Insufficient …

Background We studied the outcomes at school age in children who had participated in a
double-blind, placebo-controlled trial of early postnatal dexamethasone therapy (initiated …

Background: Dexamethasone has powerful anti-inflammatory effects and has been used to
treat established bronchopulmonary dysplasia (BPD), but it is uncertain whether the benefits …

BACKGROUND. Postnatal corticosteroids were widely used in the 1990s in an attempt to
reduce the incidence of bronchopulmonary dysplasia. However, high rates of short-term …