'Not only… but also': factors that contribute to accelerated atherosclerosis and premature coronary heart disease in systemic lupus erythematosus

IN Bruce - Rheumatology, 2005 - academic.oup.com
Premature coronary heart disease (CHD) has emerged as a major cause of morbidity and
mortality in patients with systemic lupus erythematosus (SLE). Overall SLE patients have a 5 …

Antibodies to apolipoprotein A‐I, high‐density lipoprotein, and C‐reactive protein are associated with disease activity in patients with systemic lupus erythematosus

SG O'Neill, I Giles, A Lambrianides… - Arthritis & …, 2010 - Wiley Online Library
Objective Inflammatory disease activity in patients with systemic lupus erythematosus (SLE)
may affect the development of atherosclerosis, contributing to their increased risk of …

Drivers of the immunopathogenesis in systemic lupus erythematosus

T Rose, T Dörner - Best practice & research Clinical rheumatology, 2017 - Elsevier
This review summarises a number of current insights into the pathogenesis of SLE. On the
basis of the interaction of environmental factors within a predisposed host, a chronic …

Longitudinal evaluation of lipoprotein variables in systemic lupus erythematosus reveals adverse changes with disease activity and prednisone and more favorable …

L Durcan, DA Winegar, MA Connelly, JD Otvos… - The Journal of …, 2016 - jrheum.org
Objective. Systemic lupus erythematosus (SLE) is associated with accelerated
atherosclerotic cardiovascular disease. Patients with SLE have adverse lipoprotein …

Systemic lupus erythematosus: immunopathogenesis and novel therapeutic targets

E Beccastrini, MM D'Elios, G Emmi… - International …, 2013 - journals.sagepub.com
Systemic lupus erythematosus (SLE) is the prototype of autoimmune diseases with
multiorgan involvement. SLE presents many genetic and epigenetic associations and the …

Oxidized low-density lipoprotein and β2-glycoprotein I in patients with systemic lupus erythematosus and increased carotid intima-media thickness: implications in …

LR Lopez, M Salazar-Paramo, C Palafox-Sanchez… - Lupus, 2006 - journals.sagepub.com
Oxidative stress and LDL modification (oxLDL) are early pro-atherogenic events. OxLDL
binds β2GPI producing immunogenic oxLDL/β2GPI complexes. Antibodies to these …

Autoimmunity, oxidized LDL and cardiovascular disease

J Frostegård - Autoimmunity reviews, 2002 - Elsevier
Atherosclerosis is the major cause of cardiovascular disease (CVD) and in addition to
established risk factors as smoking, hypertension, diabetes and dyslipidemia, inflammation …

Pathogenic immunity in systemic lupus erythematosus and atherosclerosis: common mechanisms and possible targets for intervention

M Wigren, J Nilsson, MJ Kaplan - Journal of internal medicine, 2015 - Wiley Online Library
Systemic lupus erythematosus (SLE) is an autoimmune disorder that primarily affects young
women and is characterized by inflammation in several organs including kidneys, skin …

Association of biological markers of activity of systemic lupus erythematosus with levels of anti-oxidized low-density lipoprotein antibodies

JM Gomez-Zumaquero, FJ Tinahones… - …, 2004 - academic.oup.com
Objectives. To study the levels of anti-oxidized low-density lipoprotein (LDL) antibodies in
patients with systemic lupus erythematosus (SLE) at two different points during the disease …

Monocyte and macrophage abnormalities in systemic lupus erythematosus

Y Li, PY Lee, WH Reeves - Archivum immunologiae et therapiae …, 2010 - Springer
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with profound effects
on multiple organ systems. In patients with SLE, the immune system is subverted to target …