Abstract Background and Objectives Honokiol, a major constituent isolated from Magnolia
officinalis, is regarded as a phytochemical marker and bioactive substance present in many …

Honokiol (2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol) and magnolol (4-Allyl-
2-(5-allyl-2-hydroxy-phenyl) phenol) are the major active polyphenol constituents of …

AIM: To explore the inhibition of honokiol and other four components of Chinese traditional
medicine on four kinds of cytochrome P450 activity in human liver microsomes (HLM) and …

Objective The purpose of this work is to evaluate the in vitro inhibitory effect of magnolol
(MN) and honokiol (HN) on rat/human cytochrome P450 (CYP) enzymes (1A2/1A2, 2D/2D6 …

Rationale Magnolol and honokiol are the main active components of Magnolia officinalis
Rehd. et Wils. The study of their interactions with liver microsomes is very important for the …

Honokiol is a bioactive component isolated from the medicinal herbs Magnolia officinalis
and Magnolia grandiflora that has antioxidative, anti-inflammatory, antithrombotic, and …

Honokiol and magnolol, the major bioactive neolignans of magnolia officinalis, are the most
important constituents of the crude drug prescriptions that are used in the therapy of …

The biotransformation of honokiol, a major constituent of the bark of Magnolia officinalis, was
investigated in rat and human livers. When isolated, rat livers were perfused with 10 µM …

Abstract Magnolol (MAG; 5, 5′-diallyl-2, 2′-biphenyldiol) is a major bioactive component
of Magnolia officinalis. We investigated the metabolic interactions of MAG with hepatic …

Honokiol, 2-(4-hydroxy-3-prop-2-enyl-phenyl)-4-prop-2-enyl-phenol, an active component of
Magnolia officinalis and Magnolia grandiflora, exerts various pharmacological activities such …