Purpose The pro-aging miRNA, miR-34a, is hyperactivated in the cardiac myocardial tissues
of patients and mice with diabetes, leading to diabetic cardiomyopathy (DCM). Increasing …

Purpose Diabetic cardiomyopathy (DCM) is a common and severe complication of diabetes.
Inflammation and oxidative stress play important roles in DCM development. Bicyclol is a …

Coronary artery disease (CAD) and cardiac hypertrophy (CH) are two main causes of
ischemic heart disease. Acute CAD may lead to left ventricular hypertrophy (LVH). Long …

Background: Diabetic cardiomyopathy (DCM), a common complication of diabetes mellitus,
eventually leads to heart failure. Carvacrol is a food additive with diverse bioactivities. We …

This article investigated the effects of pramipexole on myocardial ischemia reperfusion (I/R)
injury and its underlying mechanisms. We utilized an in vivo mouse model of myocardial I/R …

Introduction Cardiac cell apoptosis plays a crucial role in the progression of diabetic
cardiomyopathy. Recent studies have shown that fasudil, a Rho‐kinase (ROCK) inhibitor …

Pathological cardiac hypertrophy is the main determinant of the development of heart failure,
for which there is often no effective therapy. The dysregulation of autophagy is implicated in …

Objective This study was designed to explore the relationship between ginsenoside Rb1
(Grb1) and high-load heart failure (HF) in rats. Methods The parameters of cardiac systolic …

Heart failure is one of the leading causes of mortality not only in the Western world but also
in China. The key pathophysiological process that ultimately leads to heart failure is cardiac …

Diabetic cardiomyopathy (DCM) is a cardiac disorder, which affects around 12% diabetic
patients, resulting in overt heart death. Our initial bioinformatic analysis identified the …