During the past decade, cell death researchers have witnessed a gradual but deep
conceptual revolution: it has been unequivocally shown that necrosis, which for long had …

For a long time, apoptosis was considered the sole form of programmed cell death during
development, homeostasis and disease, whereas necrosis was regarded as an unregulated …

Necrosis is often viewed as an accidental and unregulated cellular event. However,
accumulating evidence suggests that necrosis, like apoptosis, can be executed by regulated …

Necroptosis | New England Journal of Medicine Skip to main content The New England Journal
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Regulated cell death is one major factor to ensure homoeostasis in multicellular organisms.
For decades, apoptosis was considered as the sole form of regulated cell death, whereas …

Apoptosis is a programmed form of cell death with well-defined morphological traits that are
often associated with activation of caspases. More recently evidence has become available …

Necroptosis is a novel form of programmed cell death that is independent of caspase
activity. Different stimuli can trigger necroptosis. At present, the most informative studies …

Necrosis, a form of death characterized by rupture of the cell membrane, is closely
interlinked with inflammation. Cellular components released during necrotic death can …

Over the past 15 years, elegant studies have demonstrated that in certain conditions,
programed cell death resembles necrosis and depends on a unique molecular pathway with …

Necroptosis refers to a regulated form of cell death induced by a variety of stimuli. Although it
has been implicated in the pathogenesis of many diseases, there is evidence to support that …