Chronic pancreatitis is uncommon in the developed world, but it exacts an inordinate toll in
terms of morbidity, mortality and health economics. 1 The control of pancreatic pain is the …

The pathogenesis of pancreatitis has remained a confused subject in spite of extensive
investigation and the advancement of numerous theories. There are two main reasons for …

The second half of this century has been marked by the evolution of specialities in some
branches of medicine, of which gastro-enterology has proved one of the more vigorous and …

To date, there is no consensus on the evolution of chronic pancreatitis. Comfort's initial
proposal of acute pancreatitis progressing to chronic pancreatitis was discarded by …

There have been few efforts to classify diseases of the pancreas by their specific
pathological features and causes. In 1946 Comfort et al'observed that the changes of acute …

Chronic pancreatitis is an irreversible condition of the pancreas characterized by chronic
progressive pancreatic inflammation, fibrosis, and scarring resulting in loss of both exocrine …

Background and aims. This review discusses current concepts regarding the etiology,
pathogenesis, diagnosis, and treatment of chronic pancreatitis. Results. Treatment of …

Chronic pancreatitis is characterized by progressive and irreversible loss of pancreatic
exocrine and endocrine function. In the majority of cases, particularly in Western …

Chronic pancreatitis has been difficult to treat because the origin, pathophysiologic
mechanisms and causes of unrelenting pain are so poorly understood. Furthermore, the …

Chronic pancreatitis (CP) is characterized by irreversible morphological and functional
alterations of the pancreas presenting clinically with upper abdominal pain as well as …