Background: Psoriasis is a chronic, autoimmune, inflammatory disease characterized by
scaly red patches on the skin that has great negative effect on quality of life. Rosuvastatin, a …

Background: Psoriasis is a T helper 1 cell-mediated chronic inflammation. Statins have been
found to have anti-inflammatory and immunomodulatory effects targeting T helper 1 cells …

Background: Psoriasis is a chronic inflammatory disease that also predisposes patients to
metabolic syndrome and its components, most prevalent of which is hyperlipidemia. Statins …

Background Considering the pathogenesis of psoriasis and also the anti‐oxidant,
immunomodulatory, and anti‐inflammatory properties of rosuvastatin and melatonin, the …

Study Objective. To explore the efficacy and safety of oral atorvastatin for the treatment of
plaque‐type psoriasis. Design. Prospective, randomized, double‐blind, placebo‐controlled …

Results Of 279 records identified, there were 5 eligible RCTs, with a total of 223 patients,
including 128 patients who received a statin (atorvastatin or simvastatin). The improvement …

Objective To determine the efficacy and safety of simvastatin in chronic plaque psoriasis.
Patients and methods Sixty patients of either sex, aged between 18 and 70 years were …

To evaluate the effect of simvastatin as an adjuvant with topical steroid on disease severity
on patients with chronic plaque psoriasis. In a double blind study, 50 patients with plaque …

Background: Psoriasis is a common dermatologic disorder, with fluctuating response to
treatment. Considering the proven immunomodulatory effects of oral simvastatin in psoriasis …

Background: Psoriasis is becoming increasingly recognized as a chronic systemic
inflammatory disease. Statins are generally well-tolerated drugs with pleiotropic effects …