T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses
D Suan, A Nguyen, I Moran, K Bourne, JR Hermes… - Immunity, 2015 - cell.com
B helper follicular T (Tfh) cells are critical for long-term humoral immunity. However, it
remains unclear how these cells are recruited and contribute to secondary immune …
remains unclear how these cells are recruited and contribute to secondary immune …
T follicular helper cell heterogeneity: time, space, and function
T follicular helper (Tfh) cells play a crucial role in orchestrating the humoral arm of adaptive
immune responses. Mature Tfh cells localize to follicles in secondary lymphoid organs (SLO …
immune responses. Mature Tfh cells localize to follicles in secondary lymphoid organs (SLO …
Follicular helper T cells as cognate regulators of B cell immunity
LJ McHeyzer-Williams, N Pelletier, L Mark… - Current opinion in …, 2009 - Elsevier
Follicular helper T (TFH) cells are a class of helper T cells specialized in the cognate control
of antigen-specific B cell immunity. Upon first contact with antigen-primed B cells …
of antigen-specific B cell immunity. Upon first contact with antigen-primed B cells …
Persistent antigen and germinal center B cells sustain T follicular helper cell responses and phenotype
T follicular helper (Tfh) cells provide help to B cells and are crucial for establishment of
germinal center (GC) reactions, including production of high-affinity antibodies and …
germinal center (GC) reactions, including production of high-affinity antibodies and …
The elusive identity of T follicular helper cells
D Yu, CG Vinuesa - Trends in immunology, 2010 - cell.com
Follicular helper T (Tfh) cells provide help to B cells and allow formation of long-lived
antibody responses. Despite an improved understanding of the molecular program that …
antibody responses. Despite an improved understanding of the molecular program that …
Follicular helper T cell differentiation requires continuous antigen presentation that is independent of unique B cell signaling
Effective humoral immunity depends on the support of B cell responses by T follicular helper
(Tfh) cells. Although it has been proposed that Tfh cell differentiation requires TB …
(Tfh) cells. Although it has been proposed that Tfh cell differentiation requires TB …
[HTML][HTML] Follicular helper T cells: lineage and location
N Fazilleau, L Mark, LJ McHeyzer-Williams… - Immunity, 2009 - cell.com
Follicular helper T (Tfh) cells are the class of effector T helper cells that regulates the step-
wise development of antigen-specific B cell immunity in vivo. Deployment of CXCR5+ Tfh …
wise development of antigen-specific B cell immunity in vivo. Deployment of CXCR5+ Tfh …
Continually recruited naïve T cells contribute to the follicular helper and regulatory T cell pools in germinal centers
J Merkenschlager, RM Berz, V Ramos, M Uhlig… - Nature …, 2023 - nature.com
Follicular helper T cells (TFH) mediate B cell selection and clonal expansion in germinal
centers (GCs), and follicular regulatory T cells (TFR) prevent the emergence of self-reactive …
centers (GCs), and follicular regulatory T cells (TFR) prevent the emergence of self-reactive …
Interconnected subsets of memory follicular helper T cells have different effector functions
A Asrir, M Aloulou, M Gador, C Pérals… - Nature …, 2017 - nature.com
Follicular helper T cells regulate high-affinity antibody production. Memory follicular helper T
cells can be local in draining lymphoid organs and circulate in the blood, but the underlying …
cells can be local in draining lymphoid organs and circulate in the blood, but the underlying …
T Follicular Helper Cell Heterogeneity
T follicular helper (Tfh) cells specialize in helping B cells and are therefore critical
contributors to the generation of humoral immunity. Tfh cells aid immunoglobulin class …
contributors to the generation of humoral immunity. Tfh cells aid immunoglobulin class …