Peptides that bind to a given major histocompatibility complex (MHC) molecule share
sequence similarity. Therefore, a position specific scoring matrix (PSSM) or profile derived …

Prediction of peptide binding to major histocompatibility complex (MHC) molecules is a
basis for anticipating T-cell epitopes. Peptides that bind to a given MHC molecule are …

The identification of MHC class II restricted peptide epitopes is an important goal in
immunological research. A number of computational tools have been developed for this …

Specific binding of antigenic peptides to major histocompatibility complex (MHC) class I
molecules is a prerequisite for their recognition by cytotoxic T-cells. Prediction of MHC …

Background A variety of methods for prediction of peptide binding to major histocompatibility
complex (MHC) have been proposed. These methods are based on binding motifs, binding …

Major histocompatibility complex class II (MHCII) molecules play an important role in cell-
mediated immunity. They present specific peptides derived from endosomal proteins for …

Considerable interest has focused on understanding how major histocompatibility complex
(MHC) specificity is generated and characterizing the specificity of MHC molecules with the …

Motivation: MHC: peptide binding plays a central role in activating the immune surveillance.
Computational approaches to determine T-cell epitopes restricted to any given major …

Major histocompatibility complex class II (MHC‐II) molecules are expressed on the surface
of professional antigen‐presenting cells where they display peptides to T helper cells, which …

Background The binding between antigenic peptides (epitopes) and the MHC molecule is a
key step in the cellular immune response. Accurate in silico prediction of epitope-MHC …