[HTML][HTML] Role of Y Box Protein-1 in cancer: As potential biomarker and novel therapeutic target
The Y-box binding protein (YB-1) is known to be a multifunctional transcription and
translation factor during expression of several proteins. It is a vital oncoprotein that regulates …
translation factor during expression of several proteins. It is a vital oncoprotein that regulates …
YB-1 as a potential target in cancer therapy
H Lage, P Surowiak, PS Holm - Der Pathologe, 2008 - Springer
The 42-kDa multifunctional cellular protein Y-box protein 1 (YB-1) is expressed in various
cancers. It is localized in the cytoplasm as well as in the nucleus. In particular, YB-1 is …
cancers. It is localized in the cytoplasm as well as in the nucleus. In particular, YB-1 is …
Elevated nuclear YB1 expression is associated with poor survival of patients with early breast cancer
A Maciejczyk, J Szelachowska, M Ekiert… - Anticancer …, 2012 - ar.iiarjournals.org
Background: Y-Box–Binding (YB1) protein represents a multifunctional protein, which plays
a significant role in processes of proliferation, apoptosis and control of tumour cell response …
a significant role in processes of proliferation, apoptosis and control of tumour cell response …
Y-box binding protein 1–a prognostic marker and target in tumour therapy
C Kosnopfel, T Sinnberg, B Schittek - European journal of cell biology, 2014 - Elsevier
Y-box binding protein 1 (YB-1) is a multifunctional protein involved in various cellular
processes including both transcriptional and translational regulation of target gene …
processes including both transcriptional and translational regulation of target gene …
YB-1: oncoprotein, prognostic marker and therapeutic target?
Hanahan and Weinberg have proposed the 'hallmarks of cancer'to cover the biological
changes required for the development and persistence of tumours [Hanahan and Weinberg …
changes required for the development and persistence of tumours [Hanahan and Weinberg …
Y-box binding protein-1 regulates cell proliferation and is associated with clinical outcomes of osteosarcoma
Y Fujiwara-Okada, Y Matsumoto, J Fukushi… - British journal of …, 2013 - nature.com
Background: Prognosis of osteosarcoma (OS) with distant metastasis and local recurrence is
still poor. Y-box binding protein-1 (YB-1) is a multifunctional protein that can act as a …
still poor. Y-box binding protein-1 (YB-1) is a multifunctional protein that can act as a …
Y-box binding protein-1 (YB-1) promotes cell cycle progression through CDC6-dependent pathway in human cancer cells
Y Basaki, K Taguchi, H Izumi, Y Murakami… - European journal of …, 2010 - Elsevier
Y-box binding protein-1 (YB-1) plays pivotal roles in acquisition of global drug resistance
and cell growth promotion through transcriptional activation of genes for both drug …
and cell growth promotion through transcriptional activation of genes for both drug …
Y‑box‑binding protein 1 inhibits apoptosis and upregulates EGFR in colon cancer
S Nagasu, T Sudo, T Kinugasa… - Oncology …, 2019 - spandidos-publications.com
Abstract Y‑box‑binding protein 1 (YB‑1) is a DNA/RNA‑binding protein and an important
transcription and translation factor in carcinogenesis. However, the biological function and …
transcription and translation factor in carcinogenesis. However, the biological function and …
YB-1 as an oncoprotein: functions, regulation, post-translational modifications, and targeted therapy
Q Yin, M Zheng, Q Luo, D Jiang, H Zhang, C Chen - Cells, 2022 - mdpi.com
Y box binding protein 1 (YB-1) is a protein with a highly conserved cold shock domain (CSD)
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …
that also belongs to the family of DNA-and RNA-binding proteins. YB-1 is present in both the …
A comprehensive review of the functions of YB-1 in cancer stemness, metastasis and drug resistance
The Y Box binding protein 1 (YB-1) is a member of the highly conserved Cold Shock Domain
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …
protein family with multifunctional properties both in the cytoplasm and inside the nucleus …
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