Background Pancreatic cancer has been characterized by poor prognosis, early metastasis
and dissatisfactory treatment outcome. The high basal level of autophagy in tumor cells …

Aims Isoliquiritigenin (ISL), a flavonoid from Glycyrrhiza glabra, has previously been
reported to have anti-tumor effects in vivo and in vitro. However, the mechanisms whereby …

Isoliquiritigenin (ISL) is a flavonoid extracted from licorice root, which is known to serve
important antitumor roles in numerous types of cancers; however, its effect on gastric cancer …

Ovarian cancer is one of the commonest gynecologic malignancies, which has a poor
prognosis for patients at the advanced stage. Isoliquiritigenin (ISL), an active flavonoid …

Isoginkgetin (ISO), a natural biflavonoid, exhibited cytotoxic activity against several types of
cancer cells. However, its effects on hepatocellular carcinoma (HCC) cells and mechanism …

Liver cancer is a leading cause of cancer death worldwide, and novel chemotherapeutic
drugs to suppress liver cancer are urgently required. Isovitexin (IV), a glycosylflavonoid, is …

Hepatocellular carcinoma (HCC) is an aggressive malignancy with high rates of metastasis
and relapse. Isoquercitrin (ISO), a natural flavonoid present in the Chinese bayberry and …

The overall survival rate of patients with hepatocellular carcinoma (HCC) has remained
unchanged over the last several decades. Therefore, novel drugs and therapies are …

Endometrial cancer is the most common cancer in women, typically with onset after
menopause. Isoliquiritigenin (ISL), a licorice flavonoid, was previously shown to have anti …

Oxidative stress could lead to a variety of body dysfunctions, including neurodegeneration
and cancer, which are closely associated with intracellular signal transducers such as …