An immune cell atlas reveals the dynamics of human macrophage specification during prenatal development

Z Wang, Z Wu, H Wang, R Feng, G Wang, M Li… - Cell, 2023 - cell.com
Macrophages are heterogeneous and play critical roles in development and disease, but
their diversity, function, and specification remain inadequately understood during human …

Tissue-resident macrophage development and function

Y Wu, KK Hirschi - Frontiers in cell and developmental biology, 2021 - frontiersin.org
Tissue-resident macrophages have been associated with important and diverse biological
processes such as native immunity, tissue homeostasis and angiogenesis during …

Biology of resident tissue macrophages

CZW Lee, F Ginhoux - Development, 2022 - journals.biologists.com
Although best known for their phagocytic and immunological functions, macrophages have
increasingly been recognised as key players in the development, homeostasis and …

Transcriptional control of monocyte and macrophage development

D Kurotaki, H Sasaki, T Tamura - International immunology, 2017 - academic.oup.com
Monocytes and macrophages play critical roles in immune responses, tissue homeostasis
and disease progression. There are a number of functionally and phenotypically distinct …

The isolation and characterization of murine macrophages

X Zhang, R Goncalves… - Current protocols in …, 2008 - Wiley Online Library
Macrophages are mononuclear phagocytes that are widely distributed throughout the body.
These cells can contribute to development and homeostasis and participate in innate and …

Macrophage immunotherapy: overcoming impediments to realize promise

LM Sly, DM McKay - Trends in Immunology, 2022 - cell.com
As an essential component of immunity, macrophages have key roles in mammalian host
defense, tissue homeostasis, and repair, as well as in disease pathogenesis and …

Macrophage Biology, Classification, and Phenotype in Cardiovascular Disease: JACC Macrophage in CVD Series (Part 1)

JW Williams, C Giannarelli, A Rahman… - Journal of the American …, 2018 - jacc.org
Macrophages represent one of the most numerous and diverse leukocyte types in the body.
Furthermore, they are important regulators and promoters of many cardiovascular disease …

Macrophage: SHIP of immunity

CD Mills, AC Thomas, LL Lenz, M Munder - Frontiers in immunology, 2014 - frontiersin.org
Immunology. Why does it exist? Two words. Cure disease. People get diseases.“Test tubes”
do not. People fund immunologists for solutions to their health problems. But, immunologists …

Signals governing monocyte differentiation during inflammation

SL Orozco, SP Canny, JA Hamerman - Current opinion in immunology, 2021 - Elsevier
Highlights•Monocyte differentiation varies widely during inflammation resulting in protective
or pathological functions.•Emergency myelopoiesis can be induced by direct or indirect …

Macrophages in tissues and in vitro

S Gordon, I Fraser, D Nath, D Hughes… - Current opinion in …, 1992 - Elsevier
Macrophages have specialized functions in different tissue microenvironments such as
lymphohaemopoietic organs and the nervous system. Recently, progress has been made in …