[HTML][HTML] Toll-like receptor agonists partially restore the production of pro-inflammatory cytokines and type I interferon in Sézary syndrome
KCG Manfrere, MP Torrealba, DR Miyashiro… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Sézary syndrome (SS) carries a poor prognosis, and infections represent the most frequent
cause of death in SS patients. Toll-like receptors (TLRs) are a family of innate immune …
cause of death in SS patients. Toll-like receptors (TLRs) are a family of innate immune …
Suppressive effects of sunitinib on a TLR activation-induced cytokine storm
S Zhao, N Gao, H Qi, H Chi, B Liu, B He, J Wang… - European Journal of …, 2019 - Elsevier
The cytokine storm includes a clinically heterogeneous set of life-threatening conditions that
are manifested by extremely elevated serum cytokine levels and related symptoms (eg …
are manifested by extremely elevated serum cytokine levels and related symptoms (eg …
Dual stimulation of MyD88-dependent Toll-like receptors induces synergistically enhanced production of inflammatory cytokines in murine bone marrow-derived …
D Mitchell, M Yong, W Schroder, M Black… - The Journal of …, 2010 - academic.oup.com
Abstract Background. Triggering Toll-like receptors (TLRs) on dendritic cells (DCs) induces
inflammatory cytokine production necessary for T helper type 1 immunity. The present study …
inflammatory cytokine production necessary for T helper type 1 immunity. The present study …
Modulation of immune responses through direct activation of Toll-like receptors to T cells
Summary Toll-like receptors (TLRs), which are a family of pattern recognition receptors
(PRRs), are involved critically in the generation and regulation of innate immunity as well as …
(PRRs), are involved critically in the generation and regulation of innate immunity as well as …
Therapeutic Toll-like receptor agonists directly influence mouse and human T cell lymphoma cell viability and cytokine secretion
A Landrigan, G Yiu, K Agarwal, PJ Utz - Leukemia & lymphoma, 2012 - Taylor & Francis
Mycosis fungoides (MF) and S é zary syndrome (SS) are the most common forms of
cutaneous T cell lymphoma (CTCL), and most frequently manifest as CD4 CD45RO …
cutaneous T cell lymphoma (CTCL), and most frequently manifest as CD4 CD45RO …
TLR4 Engagement during TLR3-Induced Proinflammatory Signaling in Dendritic Cells Promotes IL-10–Mediated Suppression of Antitumor Immunity
D Bogunovic, O Manches, E Godefroy, A Yewdall… - Cancer research, 2011 - AACR
Toll-like receptor (TLR) agonists are promising adjuvants for immune therapy of cancer, but
their potential efficacy as single or combinatorial agents has yet to be fully evaluated. Here …
their potential efficacy as single or combinatorial agents has yet to be fully evaluated. Here …
CL097, a TLR7/8 ligand, inhibits TLR-4-dependent activation of IRAK-M and BCL-3 expression
Prolonged or repeated stimulation of Toll-like receptor (TLR) 4 leads to hyporesponsiveness
of monocyte-derived macrophages, which seems to be a hallmark of immunosuppression …
of monocyte-derived macrophages, which seems to be a hallmark of immunosuppression …
Synthetic imidazoquinolines potently and broadly activate the cellular immune response of patients with cutaneous T-cell lymphoma: synergy with interferon-γ …
M Wysocka, S Newton, BM Benoit, C Introcaso… - Clinical Lymphoma and …, 2007 - Elsevier
Advanced cutaneous T-cell lymphoma (CTCL) is typically associated with a variety of
profound defects of cellular immunity, including depressed dendritic cell numbers and …
profound defects of cellular immunity, including depressed dendritic cell numbers and …
Toll like receptor 2 signaling regulates hematopoietic stem cell function and promotes G-CSF mediated HSC mobilization
A Herman, M Romine, D Monlish, LG Schuettpelz - 2014 - ashpublications.org
Toll like receptors (TLRs) are a family of pattern recognition receptors that play a central role
in pathogen recognition and shaping the innate immune response. While most of the studies …
in pathogen recognition and shaping the innate immune response. While most of the studies …
Pathogen recognition and Toll-like receptor targeted therapeutics in innate immune cells
S Tartey, O Takeuchi - International reviews of immunology, 2017 - Taylor & Francis
The innate immune system deploys a variety of pattern-recognition receptors (PRRs) which
include Toll-like receptors (TLRs), RIG-I-like receptors, NOD-like receptors, and C-type lectin …
include Toll-like receptors (TLRs), RIG-I-like receptors, NOD-like receptors, and C-type lectin …