Chimeric vaccine designs against Acinetobacter baumannii using pan genome and reverse vaccinology approaches

F Shahid, T Zaheer, ST Ashraf, M Shehroz, F Anwer… - Scientific reports, 2021 - nature.com
Abstract Acinetobacter baumannii (A. baumannii), an opportunistic, gram-negative
pathogen, has evoked the interest of the medical community throughout the world because …

Vaccinomics to Design a Multi-Epitopes Vaccine for Acinetobacter baumannii

M Ud-Din, A Albutti, A Ullah, S Ismail, S Ahmad… - International Journal of …, 2022 - mdpi.com
Antibiotic resistance (AR) is the result of microbes' natural evolution to withstand the action
of antibiotics used against them. AR is rising to a high level across the globe, and novel …

Promising Acinetobacter baumannii Vaccine Candidates and Drug Targets in Recent Years

YC Tan, C Lahiri - Frontiers in Immunology, 2022 - frontiersin.org
In parallel to the uncontrolled use of antibiotics, the emergence of multidrug-resistant
bacteria, like Acinetobacter baumannii, has posed a severe threat. A. baumannii …

A novel mRNA multi-epitope vaccine of Acinetobacter baumannii based on multi-target protein design in immunoinformatic approach

Y Xu, F Zhu, Z Zhou, S Ma, P Zhang, C Tan, Y Luo… - BMC genomics, 2024 - Springer
Acinetobacter baumannii is a gram-negative bacillus prevalent in nature, capable of thriving
under various environmental conditions. As an opportunistic pathogen, it frequently causes …

Pangenome and immuno-proteomics analysis of Acinetobacter baumannii strains revealed the core peptide vaccine targets

A Hassan, A Naz, A Obaid, RZ Paracha, K Naz… - BMC genomics, 2016 - Springer
Background Acinetobacter baumannii has emerged as a significant nosocomial pathogen
during the last few years, exhibiting resistance to almost all major classes of antibiotics …

Reverse Vaccinology Approach to Potential Vaccine Candidates Against Acinetobacter baumannii

F Shahid, ST Ashraf, A Ali - Acinetobacter baumannii: Methods and …, 2019 - Springer
Acinetobacter baumannii is a rapidly evolving pathogen that largely inhabits intensive care
units (ICU). This opportunistic, gram-negative organism has shown noteworthy taxonomic …

Delineating the Plausible Molecular Vaccine Candidates and Drug Targets of Multidrug-Resistant Acinetobacter baumannii

S Mujawar, R Mishra, S Pawar, D Gatherer… - Frontiers in cellular and …, 2019 - frontiersin.org
Nosocomial infections have become alarming with the increase of multidrug-resistant
bacterial strains of Acinetobacter baumannii. Being the causative agent in~ 80% of the …

[HTML][HTML] Putative novel B-cell vaccine candidates identified by reverse vaccinology and genomics approaches to control Acinetobacter baumannii serotypes

S Beiranvand, A Doosti, SA Mirzaei - Infection, Genetics and Evolution, 2021 - Elsevier
In the last decade, Multi-drug resistance (MDR)-associated infections of Acinetobacter
baumannii have grown worldwide. A cost-effective preventative strategy against this …

Identification of Novel Vaccine Candidates against Multidrug-Resistant Acinetobacter baumannii

DG Moriel, SA Beatson, DJ Wurpel, J Lipman… - PloS one, 2013 - journals.plos.org
Acinetobacter baumannii is an emerging opportunistic bacterium associated with
nosocomial infections in intensive care units. The alarming increase in infections caused by …

Subtractive proteomics to identify novel drug targets and reverse vaccinology for the development of chimeric vaccine against Acinetobacter baumannii

V Solanki, V Tiwari - Scientific reports, 2018 - nature.com
The emergence of drug-resistant Acinetobacter baumannii is the global health problem
associated with high mortality and morbidity. Therefore it is high time to find a suitable …