Recent trends in nanocarrier‐based targeted chemotherapy: selective delivery of anticancer drugs for effective lung, colon, cervical, and breast cancer treatment

KT Jin, ZB Lu, JY Chen, YY Liu, HR Lan… - Journal of …, 2020 - Wiley Online Library
Chemotherapy drugs are cytotoxic to tumor cells, but their lack of specificity leads to a range
of side effects. The off‐target effects of such drugs can be improved through the use of …

Nanocarriers: a reliable tool for the delivery of anticancer drugs

H Sabit, M Abdel-Hakeem, T Shoala, S Abdel-Ghany… - Pharmaceutics, 2022 - mdpi.com
Nanomedicines have gained popularity due to their potential therapeutic applications,
especially cancer treatment. Targeted nanoparticles can deliver drugs directly to cancer …

Polymeric nanoparticles for cancer therapy

S Parveen, SK Sahoo - Journal of drug targeting, 2008 - Taylor & Francis
Cancer is an ever-increasing menace that needs to be curbed soon. Though chemotherapy
is successful to some extent, the main drawbacks of chemotherapy is the limited accessibility …

Design considerations for nanotherapeutics in oncology

T Stylianopoulos, RK Jain - Nanomedicine: Nanotechnology, Biology and …, 2015 - Elsevier
Nanotherapeutics have improved the quality of life of cancer patients, primarily by reducing
the adverse effects of chemotherapeutic agents, but improvements in overall survival are …

Hybrid nanoparticles for combination therapy of cancer

C He, J Lu, W Lin - Journal of Controlled Release, 2015 - Elsevier
Nanoparticle anticancer drug delivery enhances therapeutic efficacies and reduces side
effects by improving pharmacokinetics and biodistributions of the drug payloads in animal …

Recent advances in targeted nanomedicine as promising antitumor therapeutics

S Hejmady, R Pradhan, A Alexander, M Agrawal… - Drug discovery today, 2020 - Elsevier
Highlights•Nanocarriers with the ability to target tumors are being increasingly explored.•
Nanomedicine aid in maintaining a balance between efficacy and toxicity.•Recent advances …

Cancer nanomedicine: from targeted delivery to combination therapy

X Xu, W Ho, X Zhang, N Bertrand… - Trends in molecular …, 2015 - cell.com
The advent of nanomedicine marks an unparalleled opportunity to advance the treatment of
various diseases, including cancer. The unique properties of nanoparticles (NPs), such as …

Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications

A Wicki, D Witzigmann, V Balasubramanian… - Journal of controlled …, 2015 - Elsevier
Cancer is a leading cause of death worldwide. Currently available therapies are inadequate
and spur demand for improved technologies. Rapid growth in nanotechnology towards the …

A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics

SD Steichen, M Caldorera-Moore… - European journal of …, 2013 - Elsevier
The tumor microenvironment provides unique challenges for the delivery of
chemotherapeutic agents in doses that are effective while ensuring minimal systemic …

Nanoparticle delivery of cancer drugs

AZ Wang, R Langer, OC Farokhzad - Annual review of medicine, 2012 - annualreviews.org
Nanomedicine, the application of nanotechnology to medicine, enabled the development of
nanoparticle therapeutic carriers. These drug carriers are passively targeted to tumors …