Organ development and homeostasis involve dynamic interactions between individual cells
that collectively regulate tissue architecture and function. To ensure the highest tissue …

The process of cell competition results in the elimination of cells that are viable but 'less
fit'than surrounding cells. Given the highly heterogeneous nature of our tissues, it seems …

Cell competition is a biological mechanism conserved from Drosophila to vertebrates
wherein neighboring cells compare their relative fitness status resulting in the elimination of …

Cell-competitive interactions are widespread in nature and determine the outcome of a vast
variety of biological processes. A particular class of competitive interactions takes place …

Highlights•In the epiblast, cell competition occurs between cells with different Myc
levels.•Cell competition can be a tumor suppressor mechanism by replenishing new …

Cell competition is a context‐dependent cell elimination through short‐range cell–cell
interaction, in which cells with higher fitness eliminate neighboring less‐fit or oncogenic …

The growth and survival of cells within tissues can be affected by 'cell competition'between
different cell clones. This phenomenon was initially recognized between wild-type cells and …

Multicellular organisms evolved to resolve conflicts between individual cells, protecting the
internal organization of the individual. This is illustrated by cell competition, a process that …

During embryonic development or under certain pathological conditions, viable but
suboptimal cells are often eliminated from the cellular society through a process termed cell …

Although cellular tumor-suppression mechanisms are widely studied, little is known about
mechanisms that act at the level of tissues to suppress the occurrence of aberrant cells in …