The pathological features of Alzheimer's disease (AD) include senile plaques induced by
amyloid-β (Aβ) protein deposits, neurofibrillary tangles formed by aggregates of …

Alzheimer's disease (AD) is the main cause of dementia, and β‐amyloid (Aβ) is a central
factor in the initiation and progression of the disease. Different forms of Aβ have been …

Alzheimer disease (AD) is the most common cause of age-related dementia, affecting more
than 25 million people worldwide. The accumulation of insoluble β-amyloid (Aβ) plaques in …

Alzheimer's disease (AD) is a devastating neurodegenerative disease with progressive loss
of memory and cognitive function, pathologically hallmarked by aggregates of the amyloid …

Prefibrillar oligomers of the β-amyloid peptide (Aβ) are recognized as potential mediators of
Alzheimer's disease (AD) pathophysiology. Deficits in synaptic function, neurotoxicity, and …

Soluble oligomers of amyloid-beta (Aβo) are implicated by biochemical and genetic
evidence as a trigger for Alzheimer's disease (AD) pathophysiology. A key step is Aβo …

Plasma membrane cellular prion protein (PrP C) is a high-affinity receptor for toxic soluble
amyloid-β (Aβ) oligomers that mediates synaptic dysfunction. Secreted forms of PrP C …

Alzheimer's disease is the most common form of dementia and the generation of oligomeric
species of amyloid-β is causal to the initiation and progression of it. Amyloid-β oligomers …

The prion protein (PrP) is best known for its association with prion diseases. However, a
controversial new role for PrP in Alzheimer disease (AD) has recently emerged. In vitro …

Abstract Alzheimer's disease (AD), the most common neurodegenerative disorder, goes
along with extracellular amyloid‐β (Aβ) deposits. The cognitive decline observed during AD …