The discovery that botanical cannabinoids such as delta-9 tetrahydrocannabinol exert some
of their effect through binding specific cannabinoid receptor sites has led to the discovery of …

It is now known that there are at least two types of cannabinoid receptors. These are CB1
receptors, present mainly on central and peripheral neurones, and CB2 receptors, present …

Mammalian tissues contain at least two types of cannabinoid receptor, CB 1, found mainly
on neurones and CB 2, found mainly in immune cells. Endogenous ligands for these …

Alterations in the endogenous cannabinoid system have been described in almost every
category of disease. These changes can alternatively be protective or maladaptive, such as …

Abstract Cannabinoid receptors type 1 (CB 1) and type 2 (CB 2) are promising targets for a
number of diseases, including obesity, neuropathic pain, and multiple sclerosis, among …

Since the discovery of an endogenous cannabinoid system, research into the pharmacology
and therapeutic potential of cannabinoids has steadily increased. Two subtypes of G-protein …

The endocannabinoid system is a complex neuronal system involved in a number of
biological functions, like attention, anxiety, mood, memory, appetite, reward, and immune …

Cannabinoid Receptor 1 (CB1), an abundant G-protein coupled receptor in the CNS, is
currently of significant interest as a therapeutic target. Although the cellular control of …

The active principle in marijuana, Δ9-tetrahydrocannabinol (THC), has been shown to have
wide therapeutic application for a number of important medical conditions, including pain …

The cannabinoid receptor type 2 (CB2) is a class A GPCR that was cloned in 1993 while
looking for an alternative receptor that could explain the pharmacological properties of Δ9 …