Background. Placental malaria is caused by Plasmodium falciparum–infected erythrocytes
(IEs) that surface-express VAR2CSA and bind chondroitin sulfate A. The inflammatory …

Two vaccines based on Plasmodium falciparum protein VAR2CSA are currently in clinical
evaluation to prevent placental malaria (PM), but a deeper understanding of var2csa …

Malaria in pregnancy is responsible for maternal anaemia, low-birth-weight babies and
infant deaths. Plasmodium falciparum infected erythrocytes are thought to cause placental …

PURPOSE OF THE RESEARCH: VAR2CSA is considered as the main target of protective
immunity against pregnancy-associated malaria. VAR2CSA high molecular weight …

Plasmodium falciparum–infected erythrocytes bind to chondroitin sulfate A (CSA) in the
placenta via the VAR2CSA protein, a member of the P. falciparum erythrocyte membrane …

Pregnancy-associated malaria is caused by Plasmodium falciparum malaria parasites
binding specifically to chondroitin sulfate A in the placenta. This sequestration of parasites is …

Pregnancy‐associated malaria (PAM) is caused by Plasmodium falciparum‐infected
erythrocytes (IEs) that bind to chondroitin sulphate A (CSA) in the placenta by PAM …

The Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family mediates
parasite sequestration in small capillaries through tissue-specific cytoadherence. The best …

Placental malaria (PM) due to Plasmodium falciparum is a major cause of maternal, fetal
and infant mortality, but the mechanisms of pathogenesis and protective immunity are …

VAR2CSA mediates sequestration of Plasmodium falciparum-infected erythrocytes in the
placenta, increasing the risk of poor pregnancy outcomes. Naturally acquired antibodies …