[HTML][HTML] A conformational epitope in placental malaria vaccine antigen VAR2CSA: What does it teach us?
JYA Doritchamou, JP Renn, L Hviid, PE Duffy - PLoS Pathogens, 2023 - journals.plos.org
VAR2CSA is the Plasmodium falciparum variant surface antigen that mediates binding of
infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous …
infected erythrocytes to chondroitin sulfate A (CSA) and their sequestration in intervillous …
Functional and Immunological Characterization of a Duffy Binding–Like–γ Domain from Plasmodium falciparum Erythrocyte Membrane Protein–1 Expressed by a …
YS Chia, C Badaut, NG Tuikue Ndam… - The Journal of …, 2005 - academic.oup.com
A recombinant Duffy binding–like (DBL)–γ domain from a previously identified placental
isolate, 732, was expressed by use of the baculovirus/insect cell system and was purified in …
isolate, 732, was expressed by use of the baculovirus/insect cell system and was purified in …
[HTML][HTML] A new method for sequencing the hypervariable Plasmodium falciparum gene var2csa from clinical samples
Background VAR2CSA, a member of the Plasmodium falciparum erythrocyte membrane
protein 1 (PfEMP1) family, mediates the binding of P. falciparum-infected erythrocytes to …
protein 1 (PfEMP1) family, mediates the binding of P. falciparum-infected erythrocytes to …
High levels of antibodies to multiple domains and strains of VAR2CSA correlate with the absence of placental malaria in Cameroonian women living in an area of high …
YL Tutterrow, M Avril, K Singh, CA Long… - Infection and …, 2012 - Am Soc Microbiol
Placental malaria, caused by sequestration of Plasmodium falciparum-infected erythrocytes
in the placenta, is associated with increased risk of maternal morbidity and poor birth …
in the placenta, is associated with increased risk of maternal morbidity and poor birth …
Evasion of immunity to Plasmodium falciparum malaria by IgM masking of protective IgG epitopes in infected erythrocyte surface-exposed PfEMP1
L Barfod, MB Dalgaard, ST Pleman… - Proceedings of the …, 2011 - National Acad Sciences
Plasmodium falciparum malaria is a major cause of mortality and severe morbidity. Its
virulence is related to the parasite's ability to evade host immunity through clonal antigenic …
virulence is related to the parasite's ability to evade host immunity through clonal antigenic …
[HTML][HTML] Differential adhesion-inhibitory patterns of antibodies raised against two major variants of the NTS-DBL2X region of VAR2CSA
J Doritchamou, P Bigey, MA Nielsen, S Gnidehou… - Vaccine, 2013 - Elsevier
Background VAR2CSA is a large polymorphic Plasmodium falciparum protein expressed on
infected erythrocytes (IE) that allows their binding in the placenta, thus precipitating …
infected erythrocytes (IE) that allows their binding in the placenta, thus precipitating …
The NTS-DBL2X Region of VAR2CSA Induces Cross-Reactive Antibodies That Inhibit Adhesion of Several Plasmodium falciparum Isolates to Chondroitin Sulfate A
P Bigey, S Gnidehou, J Doritchamou… - Journal of Infectious …, 2011 - academic.oup.com
Background. Binding to chondroitin sulfate A by VAR2CSA, a parasite protein expressed on
infected erythrocytes, allows placental sequestration of Plasmodium falciparum–infected …
infected erythrocytes, allows placental sequestration of Plasmodium falciparum–infected …
[HTML][HTML] Towards a vaccine against Plasmodium vivax malaria
Towards a Vaccine against Plasmodium vivax Malaria | PLOS Medicine Skip to main content
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Nonimmune immunoglobulin binding and multiple adhesion characterize Plasmodium falciparum-infected erythrocytes of placental origin
N Rasti, F Namusoke, A Chêne… - Proceedings of the …, 2006 - National Acad Sciences
The harmful effects of pregnancy-associated malaria (PAM) are engendered by the heavy
sequestration of Plasmodium falciparum-parasitized RBCs in the placenta. It is well …
sequestration of Plasmodium falciparum-parasitized RBCs in the placenta. It is well …
Functional antibodies against VAR2CSA in nonpregnant populations from colombia exposed to Plasmodium falciparum and Plasmodium vivax
S Gnidehou, J Doritchamou, EM Arango… - Infection and …, 2014 - Am Soc Microbiol
In pregnancy, parity-dependent immunity is observed in response to placental infection with
Plasmodium falciparum. Antibodies recognize the surface antigen, VAR2CSA, expressed on …
Plasmodium falciparum. Antibodies recognize the surface antigen, VAR2CSA, expressed on …