During development, the interaction of stem cell factor (SCF) with its receptor, KIT, is critical
for the survival of melanocytes. Limited in vivo human studies have suggested a possible …

Melanocytes are derived from neural crest and migrate along the dorsolateral pathway to
colonize the final destination in the skin. Stem cell factor and its receptor c-kit were identified …

The growth and differentiation of mast cells and melanocytes require stem cell factor (SCF),
the ligand for the kit receptor tyrosine kinase. SCF may exist as a membrane-bound or …

Previous findings indicate that the protein c-KIT and its ligand, stem cell factor (SCF) play a
crucial role in the development of melanocytes from their precursors in the embryonic neural …

In mammalian skin, stem cell factor (SCF) regulates the proliferation and maturation of mast
cells and melanocytes, which are thought to be the only cutaneous cells that express the Kit …

The interaction of stem cell factor with its receptor, c-kit, is well known to be critical to the
survival of melanocytes. Little is known about the role (s) of the stem cell factor/c-kit …

Background The pathogenesis of melasma has not yet been clearly demonstrated. We tried
to determine whether the stem cell factor (SCF) and its receptor c‐kit are involved in the …

The cKit receptor plays a critical role in melanocyte physiology, influencing melanogenesis,
proliferation, migration, and survival of the pigment-producing cells. However, pathways of …

Kit‐ligand (Kitl) also known as steel factor, stem cell factor and mast cell growth factor plays
a crucial role in the development and maintenance of the melanocyte lineage in adult skin …

Mutations at the murine dominant white spotting (Kit W) and steel (Mgf Sl) loci, encoding c-
Kit receptor kinase and its ligand respectively, exert developmental defects on …