Adipocytes, the major cell type within adipose tissue, are key endocrine and secretory cells.
Not only do adipocytes store fatty acids as fuel, but they also synthesize and secrete a wide …

Adipocytes are the main constituent of adipose tissue and are considered to be a corner
stone in the homeostatic control of whole body metabolism. Their primary function is to …

White adipose tissue (WAT) is a major endocrine and secretory organ, which releases a
wide range of protein signals and factors termed adipokines. A number of adipokines …

Obesity, a worldwide epidemic, confers increased risk for multiple serious conditions,
including type 2 diabetes, cardiovascular diseases, nonalcoholic fatty liver disease and …

Fat is either white or brown, the latter being found principally in neonates. White fat, which
comprises adipocytes, pre-adipocytes, macrophages, endothelial cells, fibroblasts, and …

Adipose tissue evolved to efficiently store energy for times of caloric restriction. The large
caloric excess common in many Western diets has negated the need for this thrifty function …

Obesity is characterized by the chronic low-grade activation of the innate immune system. In
this respect, macrophage-elicited metabolic inflammation and adipocyte-macrophage …

This review summarizes the role of macrophages in adipose tissue remodeling, particularly
focusing on the paracrine loop between adipocytes and macrophages. The adipose tissue …

Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review
how fuel partitioning between adipocytes and other tissues affects insulin signaling …

Adipose tissue is no longer considered to be an inert tissue that stores fat. This tissue is
capable of expanding to accommodate increased lipids through hypertrophy of existing …