Hepatocellular carcinoma (HCC) is the major histological form of primary liver cancer. It has
usually reached the disease state once the patient is diagnosed since there are no specific …

Background: Hepatocellular Carcinoma (HCC) is one of the most common malignant
tumors. Due to the insidious onset and poor prognosis, most patients have reached the …

Background Early detection of complex diseases like hepatocellular carcinoma remains
challenging due to their network-driven pathology. Dynamic network biomarkers (DNB) …

Page 2 of 3 recently reported the effect of the dynamic network biomarker (DNB) method in
developing a new biomarker for identifying the tipping point of HCC to metastasize (24) …

Hepatocellular carcinoma (HCC) is a complex disease with a multi-step carcinogenic
process from preneoplastic lesions, including cirrhosis, low-grade dysplastic nodules …

Dynamic network biomarkers (DNB) can identify the critical state or tipping point of a
disease, thereby predicting rather than diagnosing the disease. However, it is difficult to …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors and is a
serious threat to human health; thus, early diagnosis and adequate treatment are essential …

ABSTRACT A new model-free method has been developed and termed the landscape
dynamic network biomarker (l-DNB) methodology. The method is based on bifurcation …

Hepatocellular carcinoma (HCC) is a malignant tumor with high mortality. This study aimed
to build a prognostic signature for HCC patients based on immune-related genes (IRGs) and …

The dynamic network biomarker (DNB) method has advanced since it was first proposed.
This review discusses advances in the DNB method that can identify the dynamic change in …