[HTML][HTML] The anti-proliferative effect of boron neutron capture therapy in a prostate cancer xenograft model

K Takahara, T Inamoto, K Minami, Y Yoshikawa… - PloS one, 2015 - journals.plos.org
Purpose Boron neutron capture therapy (BNCT) is a selective radiation treatment for tumors
that preferentially accumulate drugs carrying the stable boron isotope, 10B. BNCT has been …

[HTML][HTML] Boron delivery agents for neutron capture therapy of cancer

RF Barth, P Mi, W Yang - Cancer Communications, 2018 - Springer
Boron neutron capture therapy (BNCT) is a binary radiotherapeutic modality based on the
nuclear capture and fission reactions that occur when the stable isotope, boron-10, is …

Initiatives toward clinical boron neutron capture therapy in Japan

A Matsumura, T Asano, K Hirose, H Igaki… - Cancer biotherapy & …, 2023 - liebertpub.com
Boron neutron capture therapy (BNCT) has been performed at nuclear research reactors for
many years. The development of accelerators for BNCT resulted in a paradigm shift from …

[HTML][HTML] Response of Normal Tissues to Boron Neutron Capture Therapy (BNCT) with 10B-Borocaptate Sodium (BSH) and 10B-Paraboronophenylalanine (BPA)

H Fukuda - Cells, 2021 - mdpi.com
Boron neutron capture therapy (BNCT) is a cancer-selective radiotherapy that utilizes the
cancer targeting 10B-compound. Cancer cells that take up the compound are substantially …

10B-editing 1H-detection and 19F MRI strategies to optimize boron neutron capture therapy

S Capuani, P Porcari, F Fasano, R Campanella… - Magnetic resonance …, 2008 - Elsevier
Boron neutron capture therapy (BNCT) is a binary radiation therapy used to treat malignant
brain tumours. It is based on the nuclear reaction (10B+ nth→[11B*]→ α+ 7Li+ 2.79 MeV) …

[HTML][HTML] Comparison of the pharmacokinetics between L-BPA and L-FBPA using the same administration dose and protocol: A validation study for the theranostic …

T Watanabe, Y Hattori, Y Ohta, M Ishimura… - BMC cancer, 2016 - Springer
Background Boron neutron capture therapy (BNCT) is a cellular-level particle radiation
therapy that combines the selective delivery of boron compounds to tumour tissue with …

A theranostic approach based on the use of a dual boron/Gd agent to improve the efficacy of Boron Neutron Capture Therapy in the lung cancer treatment

D Alberti, N Protti, A Toppino, A Deagostino… - … , Biology and Medicine, 2015 - Elsevier
This study aims at developing an innovative theranostic approach for lung tumor and
metastases treatment, based on Boron Neutron Capture Therapy (BNCT). It relies on to the …

A Monte Carlo study of SPECT in boron neutron capture therapy for a heterogeneous human phantom

C Gong, X Tang, S Fatemi, H Yu… - … Journal of Radiation …, 2018 - search.proquest.com
Boron neutron capture therapy (BNCT) is a binary radiotherapy combining biochemical
targeting with neutron irradiation. However, monitoring the boron distribution is a …

[HTML][HTML] A novel approach to design and evaluate BNCT neutron beams combining physical, radiobiological, and dosimetric figures of merit

I Postuma, S González, MS Herrera, L Provenzano… - Biology, 2021 - mdpi.com
Simple Summary Clinical potential and safety are presented as novel criteria to evaluate
neutron beams designed for boron neutron capture therapy (BNCT). The presently used …

Assessment of biological effectiveness of boron neutron capture therapy in primary and metastatic melanoma cell lines

AE Rossini, MA Dagrosa, A Portu… - … journal of radiation …, 2015 - Taylor & Francis
Purpose: In order to optimize the effectiveness of Boron Neutron Capture Therapy (BNCT),
Relative Biological Effectiveness (RBE) and Compound Biological Effectiveness (CBE) were …