DrugBank 3.0: a comprehensive resource for 'omics' research on drugs

C Knox, V Law, T Jewison, P Liu, S Ly… - Nucleic acids …, 2010 - academic.oup.com
Abstract DrugBank (http://www. drugbank. ca) is a richly annotated database of drug and
drug target information. It contains extensive data on the nomenclature, ontology, chemistry …

DrugBank: a knowledgebase for drugs, drug actions and drug targets

DS Wishart, C Knox, AC Guo, D Cheng… - Nucleic acids …, 2008 - academic.oup.com
DrugBank is a richly annotated resource that combines detailed drug data with
comprehensive drug target and drug action information. Since its first release in 2006 …

DrugBank 4.0: shedding new light on drug metabolism

V Law, C Knox, Y Djoumbou, T Jewison… - Nucleic acids …, 2014 - academic.oup.com
Abstract DrugBank (http://www. drugbank. ca) is a comprehensive online database
containing extensive biochemical and pharmacological information about drugs, their …

DrugBank 6.0: the DrugBank knowledgebase for 2024

C Knox, M Wilson, CM Klinger, M Franklin… - Nucleic acids …, 2024 - academic.oup.com
First released in 2006, DrugBank (https://go. drugbank. com) has grown to become the 'gold
standard'knowledge resource for drug, drug–target and related pharmaceutical information …

DrugBank: a comprehensive resource for in silico drug discovery and exploration

DS Wishart, C Knox, AC Guo, S Shrivastava… - Nucleic acids …, 2006 - academic.oup.com
DrugBank is a unique bioinformatics/cheminformatics resource that combines detailed drug
(ie chemical) data with comprehensive drug target (ie protein) information. The database …

DrugCentral: online drug compendium

O Ursu, J Holmes, J Knockel, CG Bologa… - Nucleic acids …, 2016 - academic.oup.com
Abstract DrugCentral (http://drugcentral. org) is an open-access online drug compendium.
DrugCentral integrates structure, bioactivity, regulatory, pharmacologic actions and …

SuperTarget and Matador: resources for exploring drug-target relationships

S Günther, M Kuhn, M Dunkel, M Campillos… - Nucleic acids …, 2007 - academic.oup.com
The molecular basis of drug action is often not well understood. This is partly because the
very abundant and diverse information generated in the past decades on drugs is hidden in …

DrugMAP: molecular atlas and pharma-information of all drugs

F Li, J Yin, M Lu, M Mou, Z Li, Z Zeng, Y Tan… - Nucleic acids …, 2023 - academic.oup.com
The efficacy and safety of drugs are widely known to be determined by their interactions with
multiple molecules of pharmacological importance, and it is therefore essential to …

Pharmacogenomic biomarkers: new tools in current and future drug therapy

SC Sim, M Ingelman-Sundberg - Trends in pharmacological sciences, 2011 - cell.com
The rapid development of techniques in the area of genome analysis has facilitated
identification of new pharmacogenomic biomarkers that can provide predictive tools for …

'Metabolite-likeness' as a criterion in the design and selection of pharmaceutical drug libraries

PD Dobson, Y Patel, DB Kell - Drug discovery today, 2009 - Elsevier
Present drug screening libraries are constrained by biophysical properties that predict
desirable pharmacokinetics and structural descriptors of 'drug-likeness' or 'lead-likeness' …