T. cruzi has a complex life cycle involving four developmental stages namely, epimastigotes,
metacyclic trypomastigotes, amastigotes and bloodstream trypomastigotes. Although …

One of the more accepted concepts in our understanding of the biology of early
Trypanosoma cruzi–host cell interactions is that the mammalian-infective trypomastigote …

Among the different infective stages that Trypanosoma cruzi employs to invade cells,
extracellular amastigotes (EAs) have recently gained attention by our group. This is true …

The protozoan parasite Trypanosoma cruzi has a complex biological cycle that involves
vertebrate and invertebrate hosts. In mammals, the infective trypomastigote form of this …

Trypanosoma cruzi, the causative agent of Chagas disease, is transmitted to vertebrate
hosts by blood-sucking insects. This protozoan is an obligate intracellular parasite. The …

Since the discovery of Trypanosoma cruzi and the brilliant description of the then-referred to"
new tripanosomiasis" by Carlos Chagas 100 years ago, a great deal of scientific effort and …

The protozoan parasite Trypanosoma cruzi, the etiologic agent of Chagas disease, is an
obligate intracellular protozoan pathogen. Overlapping mechanisms ensure successful …

Mammalian cell invasion by Trypanosoma cruzi is a complex process in which various
parasite and host cell components interact, triggering the activation of signaling cascades …

Chagas disease is caused by the kinetoplastid parasite Trypanosoma cruzi, which is mainly
transmitted by hematophagous insect bites. The parasite's lifecycle has an obligate …

Mammalian cell invasion by the protozoan pathogen Trypanosoma cruzi is critical to its
survival in the host. To promote its entry into a wide variety of non‐professional phagocytic …