[HTML][HTML] The perfect bacteriophage for therapeutic applications—a quick guide

L Fernández, D Gutiérrez, P García, A Rodríguez - Antibiotics, 2019 - mdpi.com
The alarming spread of multiresistant infections has kick-started the quest for alternative
antimicrobials. In a way, given the steady increase in untreatable infectious diseases …

[HTML][HTML] Phage-derived antibacterials: harnessing the simplicity, plasticity, and diversity of phages

B Kim, ES Kim, YJ Yoo, HW Bae, IY Chung, YH Cho - Viruses, 2019 - mdpi.com
Despite the successful use of antibacterials, the emergence of multidrug-resistant bacteria
has become a serious threat to global healthcare. In this era of antibacterial crisis …

[HTML][HTML] Engineered bacteriophage therapeutics: rationale, challenges and future

M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Back to the future: bacteriophages as promising therapeutic tools

P Domingo‐Calap, P Georgel, S Bahram - Hla, 2016 - Wiley Online Library
Bacteriophages (phages), natural predators of bacteria, are becoming increasingly attractive
in medical and pharmaceutical applications. After their discovery almost a century ago, they …

Phage therapy: awakening a sleeping giant

DR Roach, L Debarbieux - Emerging Topics in Life Sciences, 2017 - portlandpress.com
For a century, bacterial viruses called bacteriophages have been exploited as natural
antibacterial agents. However, their medicinal potential has not yet been exploited due to …

[HTML][HTML] Phage therapy: combating infections with potential for evolving from merely a treatment for complications to targeting diseases

A Górski, R Międzybrodzki… - Frontiers in …, 2016 - frontiersin.org
Antimicrobial resistance is considered to be one of the greatest challenges of medicine and
our civilization. Lack of progress in developing new anti-bacterial agents has greatly revived …

[HTML][HTML] Current clinical landscape and global potential of bacteriophage therapy

NM Hitchcock, D Devequi Gomes Nunes, J Shiach… - Viruses, 2023 - mdpi.com
In response to the global spread of antimicrobial resistance, there is an increased demand
for novel and innovative antimicrobials. Bacteriophages have been known for their potential …

[HTML][HTML] Bacteriophages: protagonists of a post-antibiotic era

P Domingo-Calap, J Delgado-Martínez - Antibiotics, 2018 - mdpi.com
Despite their long success for more than half a century, antibiotics are currently under the
spotlight due to the emergence of multidrug-resistant bacteria. The development of new …

[HTML][HTML] Phage therapeutics: from promises to practices and prospectives

K Bhargava, G Nath, A Bhargava, GK Aseri… - Applied Microbiology and …, 2021 - Springer
The rise in multi-drug resistant bacteria and the inability to develop novel antibacterial
agents limits our arsenal against infectious diseases. Antibiotic resistance is a global issue …

[HTML][HTML] Bacteriophage procurement for therapeutic purposes

B Weber-Dąbrowska, E Jończyk-Matysiak… - Frontiers in …, 2016 - frontiersin.org
Bacteriophages (phages), discovered 100 years ago, are able to infect and destroy only
bacterial cells. In the current crisis of antibiotic efficacy, phage therapy is considered as a …