The sperm mitochondrion: Organelle of many functions

CR Moraes, S Meyers - Animal reproduction science, 2018 - Elsevier
This review summarizes current research in sperm mitochondrial function with specific
emphasis on mitochondrial metabolism, reactive oxygen species production and …

Mitochondria as regulatory forces in oocytes, preimplantation embryos and stem cells

J Van Blerkom - Reproductive biomedicine online, 2008 - Elsevier
In addition to their role in generating energy (ATP), other possible regulatory functions for
mitochondria in the mature oocyte, preimplantation stage embryo and differentiating …

Mitochondrial regulation during male germ cell development

X Wang, L Yin, Y Wen, S Yuan - Cellular and Molecular Life Sciences, 2022 - Springer
Mitochondria tailor their morphology to execute their specialized functions in different cell
types and/or different environments. During spermatogenesis, mitochondria undergo …

Mitochondria, spermatogenesis and male infertility

S Rajender, P Rahul, AA Mahdi - Mitochondrion, 2010 - Elsevier
Mitochondria and its role in male reproduction has remained an enigma since long.
Similarly, etiology of male infertility in a large percentage of individuals, mainly primary …

Mitochondrial reactive oxygen species (ROS) production alters sperm quality

R Chianese, R Pierantoni - Antioxidants, 2021 - mdpi.com
Besides ATP production, mitochondria are key organelles in several cellular functions, such
as steroid hormone biosynthesis, calcium homoeostasis, intrinsic apoptotic pathway, and the …

The role of mitochondrial activity in female fertility and assisted reproductive technologies: overview and current insights

GN Cecchino, E Seli, ELA da Motta… - Reproductive …, 2018 - Elsevier
Mitochondria have been implicated as key factors regulating female reproductive processes.
Notable progress has been made in determining the role of mitochondria with respect to …

Mitochondrial dysfunction in reproduction

RPS Jansen, GJ Burton - Mitochondrion, 2004 - Elsevier
The mitochondrial genome passes from one generation to the next by way of the egg's
cytoplasm, so ordinarily an individual's mitochondrial DNA (mtDNA) is entirely derived from …

Mitochondrial dynamics during spermatogenesis

G Varuzhanyan, DC Chan - Journal of cell science, 2020 - journals.biologists.com
Mitochondrial fusion and fission (mitochondrial dynamics) are homeostatic processes that
safeguard normal cellular function. This relationship is especially strong in tissues with …

Pathophysiology of mitochondrial dysfunction in human spermatozoa: focus on energetic metabolism, oxidative stress and apoptosis

C Castellini, S D'Andrea, G Cordeschi, M Totaro… - Antioxidants, 2021 - mdpi.com
The dogma of mitochondria as the major source of energy in supporting sperm motility
should be critically reconsidered in the light of several experimental data pointing to a major …

Mitochondria: participation to infertility as source of energy and cause of senescence

M Benkhalifa, YJ Ferreira, H Chahine, N Louanjli… - The international journal …, 2014 - Elsevier
Mitochondria is a powerhouse organelle involved in ATP synthesis, calcium signaling,
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …