Mitochondria: participation to infertility as source of energy and cause of senescence

M Benkhalifa, YJ Ferreira, H Chahine, N Louanjli… - The international journal …, 2014 - Elsevier
Mitochondria is a powerhouse organelle involved in ATP synthesis, calcium signaling,
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …

Mitochondria, spermatogenesis, and male infertility–An update

S Vertika, KK Singh, S Rajender - Mitochondrion, 2020 - Elsevier
The incorporation of mitochondria in the eukaryotic cell is one of the most enigmatic events
in the course of evolution. This important organelle was thought to be only the powerhouse …

[HTML][HTML] Mitochondria: Their relevance during oocyte ageing

J van der Reest, GN Cecchino, MC Haigis… - Ageing Research …, 2021 - Elsevier
The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

Mitochondrial function in the human oocyte and embryo and their role in developmental competence

J Van Blerkom - Mitochondrion, 2011 - Elsevier
The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …

Mitochondria in mammalian sperm physiology and pathology: a review

FJ Pena, H Rodríguez Martínez… - … in Domestic Animals, 2009 - Wiley Online Library
Contents While, for a long time, the role of mitochondria in sperm physiology and pathology
has been largely ignored, recent research points out the mitochondria as a major organelle …

Mitochondrial dysfunction and oxidative stress caused by cryopreservation in reproductive cells

R Gualtieri, G Kalthur, V Barbato, M Di Nardo, SK Adiga… - Antioxidants, 2021 - mdpi.com
Mitochondria, fundamental organelles in cell metabolism, and ATP synthesis are
responsible for generating reactive oxygen species (ROS), calcium homeostasis, and cell …

Oocyte mitochondrial function and reproduction

E Babayev, E Seli - Current Opinion in Obstetrics and Gynecology, 2015 - journals.lww.com
Optimal energy production is required for oocyte and embryo development, and
mitochondrial abnormalities have devastating reproductive consequences. Improvement of …

Causes and consequences of sperm mitochondrial dysfunction

D Durairajanayagam, D Singh, A Agarwal… - Andrologia, 2021 - Wiley Online Library
Mitochondria have multiple functions, including synthesis of adenine triphosphate,
production of reactive oxygen species, calcium signalling, thermogenesis and apoptosis …

Mitochondria in human oogenesis and preimplantation embryogenesis: engines of metabolism, ionic regulation and developmental competence

J Van Blerkom - Reproduction, 2004 - rep.bioscientifica.com
Mitochondria are the most abundant organelles in the mammalian oocyte and early embryo.
While their role in ATP production has long been known, only recently has their contribution …

Mitochondrial DNA assessment to determine oocyte and embryo viability

E Fragouli, D Wells - Seminars in reproductive medicine, 2015 - thieme-connect.com
Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …