The role of mitochondria in energy production for human sperm motility

P Piomboni, R Focarelli, A Stendardi… - … journal of andrology, 2012 - Wiley Online Library
Mitochondria of spermatozoa are different from the corresponding organelles of somatic
cells, in both their morphology and biochemistry. The biochemical differences are essentially …

The spatio-temporal dynamics of mitochondrial membrane potential during oocyte maturation

U Al-Zubaidi, J Liu, O Cinar, RL Robker… - Molecular Human …, 2019 - academic.oup.com
Mitochondria are highly dynamic organelles and their distribution, structure and activity
affect a wide range of cellular functions. Mitochondrial membrane potential (∆ Ψm) is an …

Reproductive aging is associated with decreased mitochondrial abundance and altered structure in murine oocytes

VA Kushnir, T Ludaway, RB Russ, EJ Fields… - Journal of assisted …, 2012 - Springer
Purpose To establish the phenotype of reproductive aging in our mouse model. To test the
hypotheses that reproductive aging is associated with a decrease in mitochondrial …

Calcium signals and mitochondria at fertilisation

R Dumollard, M Duchen, C Sardet - Seminars in cell & developmental …, 2006 - Elsevier
At fertilisation, Ca2+ signals activate embryonic development by stimulating metabolism,
exocytosis and endocytosis, cytoskeletal remodelling, meiotic resumption and recruitment of …

Mitochondrial fusion is required for spermatogonial differentiation and meiosis

G Varuzhanyan, R Rojansky, MJ Sweredoski… - Elife, 2019 - elifesciences.org
Differentiating cells tailor their metabolism to fulfill their specialized functions. We examined
whether mitochondrial fusion is important for metabolic tailoring during spermatogenesis …

Mitochondrial dysfunction in mouse oocytes results in preimplantation embryo arrest in vitro

GA Thouas, AO Trounson, EJ Wolvetang… - Biology of …, 2004 - academic.oup.com
Oocyte mitochondrial dysfunction has been proposed as a cause of high levels of
developmental retardation and arrest that occur in human preimplantation embryos …

Reproductive aging is associated with changes in oocyte mitochondrial dynamics, function, and mtDNA quantity

E Babayev, T Wang, K Szigeti-Buck, K Lowther… - Maturitas, 2016 - Elsevier
Mitochondria affect numerous aspects of mammalian reproduction. We investigated whether
the decrease in oocyte quality associated with aging is related to altered mitochondria …

Mitochondrial morphology in human fetal and adult female germ cells

PM Motta, SA Nottola, S Makabe, R Heyn - Human reproduction, 2000 - academic.oup.com
The aim of this study has been to observe, by electron microscopy, the morphological
changes affecting mitochondria and associated organelles in the human female germ cell …

Mitochondrial dysfunction and ovarian aging

T Wang, M Zhang, Z Jiang, E Seli - American Journal of …, 2017 - Wiley Online Library
Mitochondria are double‐membrane‐bound organelles that are responsible for the
generation of most of the cell's energy. Mitochondrial dysfunction has been implicated in …

Mitochondria: potential roles in embryogenesis and nucleocytoplasmic transfer.

JM Cummins - Human reproduction update, 2001 - europepmc.org
This review examines current understanding of mammalian mitochondria and mitochondrial
DNA in the light of new reproductive technologies. Mitochondria are central to ageing …