Challenges in primary focal segmental glomerulosclerosis diagnosis: from the diagnostic algorithm to novel biomarkers

C Jacobs-Cachá, A Vergara… - Clinical kidney …, 2021 - academic.oup.com
Primary or idiopathic focal segmental glomerulosclerosis (FSGS) is a kidney entity that
involves the podocytes, leading to heavy proteinuria and in many cases progresses to end …

Pathophysiology and treatment of focal segmental glomerulosclerosis: the role of animal models

SML de Mik, MJ Hoogduijn, RW de Bruin, FJMF Dor - BMC nephrology, 2013 - Springer
Focal segmental glomerulosclerosis (FSGS) is a kidney disease with progressive glomerular
scarring and a clinical presentation of nephrotic syndrome. FSGS is a common primary …

Decreased glomerular filtration as the primary factor of elevated circulating suPAR levels in focal segmental glomerulosclerosis

Y Harita, K Ishizuka, A Tanego, N Sugawara… - Pediatric …, 2014 - Springer
Background Circulating factor (s) has been thought to be the underlying cause of focal
segmental glomerulosclerosis (FSGS), and recent studies foster this idea by demonstrating …

Serial estimates of serum permeability activity and clinical correlates in patients with native kidney focal segmental glomerulosclerosis

D Cattran, T Neogi, R Sharma… - Journal of the …, 2003 - journals.lww.com
A serum or plasma factor in certain patients with focal segmental glomerulosclerosis (FSGS)
has been found to increase glomerular albumin permeability (P alb) and causes proteinuria …

Diagnostic and prognostic value of soluble urokinase-type plasminogen activator receptor (suPAR) in focal segmental glomerulosclerosis and impact of detection …

W Winnicki, G Sunder-Plassmann, G Sengölge… - Scientific Reports, 2019 - nature.com
The plasma soluble urokinase-type plasminogen activator receptor (suPAR) is a biomarker
for focal segmental glomerulosclerosis (FSGS), but its value is under discussion because of …

Nephrotic focal segmental glomerulosclerosis in 2004: an update

A Meyrier - Nephrology Dialysis Transplantation, 2004 - academic.oup.com
Writing on the treatment of primary focal segmental glomerulosclerosis (FSGS) is a
challenge. The jaded nephrologist is tempted to consider that the issue could be …

Focal segmental glomerulosclerosis: towards a better understanding for the practicing nephrologist

S Sethi, RJ Glassock… - Nephrology Dialysis …, 2015 - academic.oup.com
Focal and segmental glomerulosclerosis (FSGS) is a common histopathological lesion that
can represent a primary podocytopathy, or occur as an adaptive phenomenon consequent …

Biomarkers of endothelial dysfunction in patients with primary focal segmental glomerulosclerosis

Q Zhang, C Zeng, Y Fu, Z Cheng, J Zhang, Z Liu - Nephrology, 2012 - Wiley Online Library
Aim: Endothelial dysfunction occurs in nephrotic syndrome (NS) and may constitute a link
between NS and vascular complications. Focal segmental glomerulosclerosis (FSGS) is a …

Effect of galactose on glomerular permeability and proteinuria in steroid-resistant nephrotic syndrome

K Sgambat, M Banks, A Moudgil - Pediatric Nephrology, 2013 - Springer
Background Idiopathic steroid-resistant nephrotic syndrome (SRNS) has been associated
with the presence of a circulating focal sclerosis permeability factor (FSPF) thought to …

[HTML][HTML] Familial nephropathy differing from minimal change nephropathy and focal glomerulosclerosis

AJW Branten, J Van Den Born, JLJ Jansen… - Kidney international, 2001 - Elsevier
Familial nephropathy differing from minimal change nephropathy and focal
glomerulosclerosis. Background Nephrotic syndrome in childhood is mainly due to minimal …