Advances in the elegance of chemistry in designing dendrimers

R Hourani, A Kakkar - Macromolecular rapid communications, 2010 - Wiley Online Library
Highly functional and monodisperse macromolecules with tailored architecture constitute the
key to designing efficient and smart nanomaterials. Dendrimers offer real potential to …

Cationic PAMAM dendrimers disrupt key platelet functions

CF Jones, RA Campbell, Z Franks… - Molecular …, 2012 - ACS Publications
Poly (amidoamine)(PAMAM) dendrimers have been proposed for a variety of biomedical
applications and are increasingly studied as model nanomaterials for such use. The …

Dendrimers in supramolecular chemistry: from molecular recognition to self-assembly

F Zeng, SC Zimmerman - Chemical reviews, 1997 - ACS Publications
Dendrimers, also known as arborols, or cascade, cauliflower, or starburst polymers are
attracting increasing attention because of their unique structures and properties. 1r6 These …

[HTML][HTML] Poly (amidoamine), polypropylenimine, and related dendrimers and dendrons possessing different 1→ 2 branching motifs: An overview of the divergent …

GR Newkome, CD Shreiner - Polymer, 2008 - Elsevier
This review presents an overview of 1→ 2 branched dendrimers and dendrons, created by a
divergent procedure, from their synthesis to modern day applications. The first members of …

Synthesis and functional evaluation of DNA-assembled polyamidoamine dendrimer clusters for cancer cell-specific targeting

Y Choi, T Thomas, A Kotlyar, MT Islam, JR Baker - Chemistry & biology, 2005 - cell.com
We sought to produce dendrimers conjugated to different biofunctional moieties (fluorescein
[FITC] and folic acid [FA]), and then link them together using complementary DNA …

Fabrication of zwitterionic and pH-responsive polyacetal dendrimers for anticancer drug delivery

Y Wang, D Huang, X Wang, F Yang, H Shen… - Biomaterials …, 2019 - pubs.rsc.org
Dendrimer micelles are considered to be the most promising synthetic macromolecules for
biomedical applications, but their instability in the blood circulation and undesired release at …

Multifunctional dendritic polymers in nanomedicine: opportunities and challenges

J Khandare, M Calderón, NM Dagia… - Chemical Society …, 2012 - pubs.rsc.org
Nanotechnology has resulted in materials that have greatly improved the effectiveness of
drug delivery because of their ability to control matter on the nanoscale. Advanced forms of …

Effect of size, surface charge, and hydrophobicity of poly (amidoamine) dendrimers on their skin penetration

Y Yang, S Sunoqrot, C Stowell, J Ji, CW Lee… - …, 2012 - ACS Publications
The barrier functions of the stratum corneum and the epidermal layers present a tremendous
challenge in achieving effective transdermal delivery of drug molecules. Although a few …

Designing dendrimers for drug delivery

M Liu, JMJ Fréchet - Pharmaceutical science & technology today, 1999 - Elsevier
Dendrimers are highly branched three-dimensional macromolecules with highly controlled
structures, a single molecular weight, a large number of controllable 'peripheral' …

Dendrimers and hyperbranched structures for biomedical applications

E Pedziwiatr-Werbicka, K Milowska, V Dzmitruk… - European Polymer …, 2019 - Elsevier
The use of nanotechnology in biology and medicine has been marked by rapid progress of
these industries due to the emergence of new devices, supramolecular systems, structures …