Synthesis, cellular transport, and activity of polyamidoamine dendrimer− methylprednisolone conjugates

J Khandare, P Kolhe, O Pillai, S Kannan… - Bioconjugate …, 2005 - ACS Publications
Dendrimers have emerged as promising multifunctional nanomaterials for drug delivery due
to their well-defined size and tailorability. We compare two schemes to obtain …

Hydrophobically modified poly (amidoamine)(PAMAM) dendrimers: their properties at the air–water interface and use as nanoscopic container molecules

Y Sayed-Sweet, DM Hedstrand, R Spinder… - Journal of Materials …, 1997 - pubs.rsc.org
Tri-and tetra-dendron poly (amidoamine)(PAMAM) dendrimers were converted into
hydrocarbon-soluble polymers and used as hydrophobic nanoscopic scaffolding by reacting …

Preliminary biological evaluation of polyamidoamine (PAMAM) StarburstTM dendrimers

JC Roberts, MK Bhalgat, RT Zera - Journal of Biomedical …, 1996 - Wiley Online Library
PAMAM Starburst™ dendrimers are spherical macromolecules composed of repeating
polyamidoamino units. They can be produced in successive “generations,” each with a …

Applications of dendrimers in bio-organic chemistry

Y Kim, SC Zimmerman - Current opinion in chemical biology, 1998 - Elsevier
Dendrimers represent a new class of highly branched polymers whose interior cavities and
multiple peripheral groups facilitate potential applications in biomedicine and bio-organic …

Dendrimers for pharmaceutical and biomedical applications

H Yang, WJ Kao - Journal of biomaterials science, polymer edition, 2006 - Taylor & Francis
Dendrimers are a unique class of synthetic macromolecules having a highly branched, three-
dimensional, nanoscale architecture with very low polydispersity and high functionality …

Preparation, cellular transport, and activity of polyamidoamine-based dendritic nanodevices with a high drug payload

P Kolhe, J Khandare, O Pillai, S Kannan, M Lieh-Lai… - Biomaterials, 2006 - Elsevier
Dendrimers are emerging as a relatively new class of polymeric biomaterials with
applications in drug delivery, and imaging. Achieving a high drug payload in dendrimers …

Dendrimers and other dendritic macromolecules: From building blocks to functional assemblies in nanoscience and nanotechnology

JMJ Fréchet - Journal of Polymer Science Part A: Polymer …, 2003 - Wiley Online Library
Given their size, in the single‐digit nanometer range, and the versatility of their functionality,
dendrimers and other dendritic macromolecules are poised to make a significant …

Unexpected in vivo anti-inflammatory activity observed for simple, surface functionalized poly (amidoamine) dendrimers

AS Chauhan, PV Diwan, NK Jain… - …, 2009 - ACS Publications
We report unexpected anti-inflammatory properties for naked, unmodified poly
(amidoamine)(PAMAM) dendrimers bearing simple surface functionality (eg,-NH2,-OH, etc.) …

PAMAM dendrimer based macromolecules as improved contrast agents

VJ Venditto, CAS Regino… - Molecular …, 2005 - ACS Publications
Dendrimers are an attractive platform for macromolecular imaging due to the presence of
multiple terminal groups on the exterior of the molecule. Through application of appropriate …

Recent progress in dendrimer-based nanomedicine development

Y Kim, EJ Park, DH Na - Archives of pharmacal research, 2018 - Springer
Dendrimers offer well-defined nanoarchitectures with spherical shape, high degree of
molecular uniformity, and multiple surface functionalities. Such unique structural properties …