Objective: To compare performance of contemporary aquaporin-4–immunoglobulin (Ig) G
assays in clinical service. Methods: Sera from neurologic patients (4 groups) and controls …

Objective: To define, using assays of optimized sensitivity and specificity, the most
informative specimen type for aquaporin-4 immunoglobulin G (AQP4-IgG) detection …

Objective This study was undertaken to investigate factors associated with aquaporin‐4
(AQP4)‐IgG serostatus change using a large serological database. Methods This …

Objective. Aquaporin‐4 (AQP4) serum autoantibodies are detected by a variety of methods.
The highest sensitivity is achieved with cell‐based assays, but the enzyme‐linked …

Importance Immunoglobulin G autoantibodies for aquaporin 4 (AQP4-IgG) serve as
diagnostic biomarkers for neuromyelitis optica spectrum disorder (NMOSD), and the most …

Abstract Aquaporin‐4 (AQP 4) is a water channel protein that is most highly, but not
exclusively, expressed in the central nervous system. In 2005 AQP 4 was shown to be the …

Objective To determine the sex and age distribution of aquaporin-4 (AQP4) autoimmunity
using data derived from clinical service laboratory testing of 56 464 patient samples. Design …

Abstract Background: Neuromyelitis optica (NMO, Devic syndrome) is an inflammatory
disorder of the central nervous system of putative autoimmune etiology that primarily affects …

Background The aquaporin-4 antibody (AQP4-Ab) is a disease-specific autoantibody to
neuromyelitis optica (NMO). We aimed to evaluate the accuracy of the FACS assay in …

Importance Using an aquaporin-4 (AQP4) M1-isoform–specific enzyme-linked
immunosorbent assay (ELISA) and a fixed transfected cell-based assay (CBA), we tested …