Detection of minimal residual disease state in chronic myelogenous leukemia patients using fluorescence in situ hybridization
A Amiel, S Yarkoni, S Slavin, R Or… - Cancer genetics and …, 1994 - Elsevier
Detection of minimal residual disease and relapse remain major problems in chronic
myelogenous leukemia (CML) patients following bone marrow transplantation (BMT). In …
myelogenous leukemia (CML) patients following bone marrow transplantation (BMT). In …
Competitive polymerase chain reaction as a method to detect the amplification of bcr-abl gene of chronic myeloid leukemia
F Campanini, MA Santucci, L Pattachini… - …, 2001 - haematologica.org
BACKGROUND AND OBJECTIVES: The chimeric product of the bcr-abl rearranged gene is
critical in the pathogenesis of chronic myeloid leukemia (CML), yet its role in the progression …
critical in the pathogenesis of chronic myeloid leukemia (CML), yet its role in the progression …
Characterization of genomic BCR‐ABL breakpoints in chronic myeloid leukaemia by PCR
JG Zhang, JM Goldman… - British journal of …, 1995 - Wiley Online Library
In order to understand better the mechanism of translocation between the BCR and ABL
genes in CML, we have exploited a 'bubble PCR'technique to clone genomic breakpoints …
genes in CML, we have exploited a 'bubble PCR'technique to clone genomic breakpoints …
Relationship between the type of BCR-ABL rearrangement and bone marrow histopathological features in chronic myeloid leukemia
The aim of the present study was to characterize the type of BCR-ABL transcript and to
correlate the molecular feature with bone marrow histology. For this purpose, we analysed …
correlate the molecular feature with bone marrow histology. For this purpose, we analysed …
Long persistent bcr-abl positive transcript detected by polymerase chain reaction after marrow transplant for chronic myelogenous leukemia without clinical relapse: a …
K Miyamura, T Tahara, M Tanimoto, Y Morishita… - 1993 - ashpublications.org
We report here the results of polymerase chain reaction (PCR) for bcr-abl transcript and
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …
clinical details derived from 64 chronic myelogenous leukemia (CML) patients after …
Involvement of primary mesenchymal precursors and hematopoietic bone marrow cells from chronic myeloid leukemia patients by BCR‐ABL1 fusion gene
M Chandia, JM Sayagués, ML Gutiérrez… - American Journal of …, 2014 - Wiley Online Library
For decades now, it is well established that chronic myeloid leukemia (CML) is a
hematopoietic stem cell (HPC) disorder. However, it remains to be determined whether BCR …
hematopoietic stem cell (HPC) disorder. However, it remains to be determined whether BCR …
Clonal analysis of bcr-abl rearrangement in T lymphocytes from patients with chronic myelogenous leukemia
D Jonas, M Lubbert, ES Kawasaki, M Henke, KJ Bross… - 1992 - ashpublications.org
The cytogenetic hallmark of chronic myelogenous leukemia (CML) is the Philadelphia
chromosome (Ph1), which reflects a chromosomal translocation t (9; 22) and a …
chromosome (Ph1), which reflects a chromosomal translocation t (9; 22) and a …
Molecular measurement of BCR-ABL transcript variations in chronic myeloid leukemia patients in cytogenetic remission
M Serpa, SS Sanabani, PE Dorliac-Llacer, M Conchon… - BMC Hematology, 2010 - Springer
Background The monitoring of BCR-ABL transcript levels by real-time quantitative
polymerase chain reaction (RT-qPCR) has become important to assess minimal residual …
polymerase chain reaction (RT-qPCR) has become important to assess minimal residual …
A rare, in-frame BCR-ABL fusion (e13a3) in a patient with an aggressive chronic myeloid leukaemia
IB Otazú, M Belén Rivero, R Olício, A Pinto… - Acta …, 2002 - karger.com
We have identified a rare BCR-ABL chimaeric gene with multiplex and nested RT-PCR in a
patient with an unusually aggressive chronic myeloid leukaemia. cDNA sequencing showed …
patient with an unusually aggressive chronic myeloid leukaemia. cDNA sequencing showed …