The genetics, neurogenetics and pharmacogenetics of addiction
Addictions are prevalent psychiatric disorders that confer remarkable personal and social
burden. Despite substantial evidence for their moderate, yet robust, heritability (approx …
burden. Despite substantial evidence for their moderate, yet robust, heritability (approx …
The genetics of addiction—a translational perspective
Addictions are serious and common psychiatric disorders, and are among the leading
contributors to preventable death. This selective review outlines and highlights the need for …
contributors to preventable death. This selective review outlines and highlights the need for …
Human genetics of addiction: new insights and future directions
DB Hancock, CA Markunas, LJ Bierut… - Current psychiatry …, 2018 - Springer
Abstract Purpose of Review With the advent of the genome-wide association study (GWAS),
our understanding of the genetics of addiction has made significant strides forward. Here …
our understanding of the genetics of addiction has made significant strides forward. Here …
Addiction and its brain science
R Spanagel, M Heilig - Addiction, 2005 - Wiley Online Library
Aims To illustrate how modern neurobiological approaches will help to identify the
neurocircuits and genes involved in addictive behavior. Background The current disorder …
neurocircuits and genes involved in addictive behavior. Background The current disorder …
Breaking barriers in the genomics and pharmacogenetics of drug addiction
Drug addiction remains a substantial health issue with limited treatment options currently
available. Despite considerable advances in the understanding of human genetic …
available. Despite considerable advances in the understanding of human genetic …
New insights into the genetics of addiction
MD Li, M Burmeister - Nature Reviews Genetics, 2009 - nature.com
Drug addiction is a common brain disorder that is extremely costly to the individual and to
society. Genetics contributes significantly to vulnerability to this disorder, but identification of …
society. Genetics contributes significantly to vulnerability to this disorder, but identification of …
Neuroepigenetics and addiction
DM Walker, EJ Nestler - Handbook of clinical neurology, 2018 - Elsevier
Drug addiction involves long-term behavioral abnormalities that arise in response to
repeated exposure to drugs of abuse in vulnerable individuals. It is a multifactorial syndrome …
repeated exposure to drugs of abuse in vulnerable individuals. It is a multifactorial syndrome …
Neural markers of genetic vulnerability to drug addiction
This chapter will summarize genetics findings derived from various strategies and highlight
important neural markers (or correlates) in some specific and extensively studied genes …
important neural markers (or correlates) in some specific and extensively studied genes …
The genetics of addictions: uncovering the genes
D Goldman, G Oroszi, F Ducci - Focus, 2006 - Am Psychiatric Assoc
The addictions are common chronic psychiatric diseases that today are prevented and
treated using relatively untargeted and only partially effective methods. The addictions are …
treated using relatively untargeted and only partially effective methods. The addictions are …
The role of epigenetics in addiction: clinical overview and recent updates
A Beayno, S El Hayek, P Noufi, Y Tarabay… - … Disorders: Methods and …, 2019 - Springer
Addiction is an international public health problem. It is a polygenic disorder best
understood by accounting for the interplay between genetic and environmental factors. A …
understood by accounting for the interplay between genetic and environmental factors. A …