Bilayer silk fibroin/sodium alginate scaffold promotes vascularization and advances inflammation stage in full-thickness wound

Y Shen, X Wang, Y Wang, X Guo, K Yu, K Dong… - …, 2022 - iopscience.iop.org
An ideal wound dressing for full-thickness wound regeneration should offer desirable
biocompatibility, adequate mechanical properties, barrier function, and cellular regulation …

A Biomimetic Composite Bilayer Dressing Composed of Alginate and Fibroin for Enhancing Full‐Thickness Wound Healing

Y Wang, L Su, Y Hou, F Lin, C Xu, Y Xue… - Macromolecular …, 2022 - Wiley Online Library
Full‐thickness skin wound dressings are critically important for acute cutaneous wound
healing. In this study, a bilayer sheet originating from biological macromolecules, mimicking …

[HTML][HTML] Bioactive silk fibroin scaffold with nanoarchitecture for wound healing

Q Wang, S Zhou, L Wang, R You, S Yan… - Composites Part B …, 2021 - Elsevier
Scarless skin regeneration for full-thickness wounds remains a challenge in skin tissue
engineering. The surprising scar-free repair function of fetal skin has inspired that the ideal …

Efficient wound healing using a synthetic nanofibrous bilayer skin substitute in murine model

S Arasteh, S Khanjani, H Golshahi, S Mobini… - Journal of Surgical …, 2020 - Elsevier
Abstract Treatment of full-thickness skin wounds with minimal scarring and complete
restoration of native tissue properties still exists as a clinical challenge. A bilayer skin …

Honey loaded silk fibroin 3D porous scaffold facilitates homeostatic full-thickness wound healing

M Rajput, M Mandal, A Anura, A Mukhopadhyay… - Materialia, 2020 - Elsevier
Dermal reconstruction in acute and chronic wounds needs highly vascularized dermal tissue
engineered skin substitutes which has the potentiality to provide physical cues as well as …

An innovative bi-layered wound dressing made of silk and gelatin for accelerated wound healing

S Kanokpanont, S Damrongsakkul… - International journal of …, 2012 - Elsevier
In this study, the novel silk fibroin-based bi-layered wound dressing was developed. Wax-
coated silk fibroin woven fabric was introduced as a non-adhesive layer while the sponge …

Design and fabrication of a dual protein-based trilayered nanofibrous scaffold for efficient wound healing

V Kumar, A Kumar, NS Chauhan, G Yadav… - ACS Applied Bio …, 2022 - ACS Publications
Chronic wound healing is a major threat all over the world. There are currently a plethora of
biomaterials-based wound dressings available for wound healing applications. In this study …

Fabrication and characterization of nano-fibrous bilayer composite for skin regeneration application

S Arasteh, S Kazemnejad, S Khanjani, H Heidari-Vala… - Methods, 2016 - Elsevier
Full thickness wound healing with minimal scarring and complete restoration of normal skin
properties still remains as a clinical challenge. In this study, a bilayer skin substitute has …

Anisotropic biomimetic silk scaffolds for improved cell migration and healing of skin wounds

G Lu, ZZ Ding, Y Wei, X Lu, Q Lu… - ACS applied materials & …, 2018 - ACS Publications
Improved and more rapid healing of full-thickness skin wounds remains a major clinical
need. Silk fibroin (SF) is a natural protein biomaterial that has been used in skin repair …

Keratin-and VEGF-Incorporated Honey-Based Sponge–Nanofiber Dressing: An Ideal Construct for Wound Healing

M Tavakoli, M Mirhaj, J Varshosaz… - … Applied Materials & …, 2023 - ACS Publications
To overcome the drawbacks of single-layered wound dressings, bilayer dressings are now
introduced as an alternative to achieve effective and long-term treatment. Here, a bilayer …