HDL as a biomarker, potential therapeutic target, and therapy
Emerging evidence suggests that HDL function is not always accurately predicted by HDL
choles-terol levels. The functions of HDL include reverse cholesterol transport and …
choles-terol levels. The functions of HDL include reverse cholesterol transport and …
HDL dysfunction in diabetes: causes and possible treatments
D Farbstein, AP Levy - Expert review of cardiovascular therapy, 2012 - Taylor & Francis
HDL is known to be inversely correlated with cardiovascular disease due to its diverse
antiatherogenic functions. These functions include cholesterol efflux and reverse cholesterol …
antiatherogenic functions. These functions include cholesterol efflux and reverse cholesterol …
Mechanisms of disease: proatherogenic HDL—an evolving field
It is well known that, in large populations, HDL-cholesterol levels are inversely related to the
risk of atherosclerotic clinical events; however, in an individual, the predictive value of an …
risk of atherosclerotic clinical events; however, in an individual, the predictive value of an …
The emerging role of HDL in glucose metabolism
A low plasma level of HDL cholesterol is an atherosclerotic risk factor; however, emerging
evidence suggests that low HDL levels might also contribute to the pathophysiology of type …
evidence suggests that low HDL levels might also contribute to the pathophysiology of type …
HDL in the 21st century: a multifunctional roadmap for future HDL research
A Rohatgi, M Westerterp, A Von Eckardstein… - Circulation, 2021 - Am Heart Assoc
Low high-density lipoprotein cholesterol (HDL-C) characterizes an atherogenic dyslipidemia
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …
that reflects adverse lifestyle choices, impaired metabolism, and increased cardiovascular …
HDL and cholesterol: life after the divorce?
KC Vickers, AT Remaley - Journal of lipid research, 2014 - ASBMB
For decades, HDL and HDL-cholesterol (HDL-C) levels were viewed as synonymous, and
modulation of HDL-C levels by drug therapy held great promise for the prevention and …
modulation of HDL-C levels by drug therapy held great promise for the prevention and …
HDL and type 2 diabetes: the chicken or the egg?
HDL is a complex macromolecular cluster of various components, such as apolipoproteins,
enzymes and lipids. Quality evidence from clinical and epidemiological studies led to the …
enzymes and lipids. Quality evidence from clinical and epidemiological studies led to the …
HDL, atherosclerosis, and emerging therapies
A Hafiane, J Genest - Cholesterol, 2013 - Wiley Online Library
This review aims to provide an overview on the properties of high‐density lipoproteins
(HDLs) and their cardioprotective effects. Emergent HDL therapies will be presented in the …
(HDLs) and their cardioprotective effects. Emergent HDL therapies will be presented in the …
Dysfunctional HDL in diabetes mellitus and its role in the pathogenesis of cardiovascular disease
RAK Srivastava - Molecular and cellular biochemistry, 2018 - Springer
Coronary artery disease, the leading cause of death in the developed and developing
countries, is prevalent in diabetes mellitus with 68% cardiovascular disease (CVD)-related …
countries, is prevalent in diabetes mellitus with 68% cardiovascular disease (CVD)-related …
Update on strategies to increase HDL quantity and function
D Duffy, DJ Rader - Nature Reviews Cardiology, 2009 - nature.com
Low levels of HDL cholesterol are a significant predictor of atherosclerotic cardiovascular
events. HDL is believed to protect against atherosclerosis by promoting reverse cholesterol …
events. HDL is believed to protect against atherosclerosis by promoting reverse cholesterol …