Bacterial DNA and immunostimulatory (is) synthetic CpG‐oligodeoxynucleotides (ODN) act
as adjuvants for Th1 responses and cytotoxic T cell responses to proteinaceous antigens …

Recognition of danger of infection by innate immune cells is a prerequisite to combat
infections and to activate T and B cells. Pathogenassociated molecular patterns (PAMP) play …

Some immune cells recognize distinct molecular structures present in pathogens through
specific pattern recognition receptors that are able to distinguish prokaryotic DNA from …

Unmethylated CpG motifs present in bacterial DNA rapidly trigger an innate immune
response characterized by the activation of Ig-and cytokine-secreting cells. Synthetic …

DNA vaccines can induce potent humoral and cellular immune responses without any
additional adjuvant. Recent studies indicate that unmethylated CpG dinucleotides within …

DNA containing unmethylated CpG dinucleotides (CpG DNA) is a potent activator of innate
and acquired immune responses. Although the sequence‐specific immunostimulatory …

Bacterial and synthetic DNA containing unmethylated CpG dinucleotides activate the innate
immune system and promote Th1-like immune responses. Recently, a receptor, TLR9, has …

Synthetic oligodeoxynucleotides (ODN) expressing unmethylated CpG motifs stimulate an
innate immune response characterized by the production of polyreactive immunoglobulin M …

Bacterial DNA and the synthetic CpG-oligodeoxynucleotides (ODNs) derived thereof have
attracted attention because they activate cells of the adaptive immune system (lymphocytes) …

Synthetic oligodeoxynucleotides (ODN) containing unmethylated deoxycytosine–
deoxyguanosine (CpG) motifs are very potent inducers of the innate immune system …