Surface charge affects cellular uptake and intracellular trafficking of chitosan-based nanoparticles

ZG Yue, W Wei, PP Lv, H Yue, LY Wang… - …, 2011 - ACS Publications
Chitosan-based nanoparticles (NPs) are widely used in drug delivery, device-based
therapy, tissue engineering, and medical imaging. In this aspect, a clear understanding of …

Uniform core–shell nanoparticles with thiolated hyaluronic acid coating to enhance oral delivery of insulin

H Tian, Z He, C Sun, C Yang, P Zhao… - Advanced …, 2018 - Wiley Online Library
Oral delivery of protein drugs is an attractive route of administration due to its convenience
for repeated dosing and good patient compliance. However, currently oral protein …

Hybrids of Polysaccharides and Inorganic Nanoparticles: From Morphological Design to Diverse Biomedical Applications

N Zhao, Z Jiao, L Chen, Z Liu, X Zhao… - Accounts of Materials …, 2023 - ACS Publications
Conspectus As widespread natural polymers with biocompatibility, biodegradability, and
bioactivity properties, polysaccharides are considered ideal candidates to fabricate …

Size-dependent absorption mechanism of polymeric nanoparticles for oral delivery of protein drugs

C He, L Yin, C Tang, C Yin - Biomaterials, 2012 - Elsevier
Polymeric nanoparticles have been widely applied to oral delivery of protein drugs,
however, few studies focused on the systematical elucidation of the size-dependent oral …

Time-Resolved Study on Self-Assembling Behavior of PEGylated Gold Nanoparticles in the Presence of Human Serum Albumin: A System for Nanomedical …

N Iranpour Anaraki, M Liebi, K Iranshahi… - ACS Applied Nano …, 2022 - ACS Publications
The combination of a microfluidic approach for synchrotron-based dynamic (early structural
changes) with lab-based static small-angle X-ray scattering (SAXS) measurements (longer …

Self-assembled reduced albumin and glycol chitosan nanoparticles for paclitaxel delivery

MA Razi, R Wakabayashi, M Goto, N Kamiya - Langmuir, 2019 - ACS Publications
Cancer continues to pose health problems for people all over the world. Nanoparticles (NPs)
have emerged as a promising platform for effective cancer chemotherapy. NPs formed by …

Stabilization of chitosan-based polyelectrolyte nanoparticle cargo delivery biomaterials by a multiple ionic cross-linking strategy

M Motiei, V Sedlařík, LA Lucia, H Fei, L Münster - Carbohydrate polymers, 2020 - Elsevier
Abstract PolyElectrolyte Nanoparticles (PENs) obtained by layer-by-layer self-assembly of
polycations/polyanions suffer from a lack of colloidal stability in physiological conditions. We …

Protein-Based Nanocarriers

S Noore, S Pathania, P Fuciños, CP O'Donnell… - … for Controlled Release …, 2024 - Springer
Protein-based nanoencapsulation possesses a higher compound/drug loading capacity
than other nanostructures. It improves the absorption and bioavailability of the encapsulated …

Self-assembled polysaccharide nanostructures for controlled-release applications

JM Myrick, VK Vendra, S Krishnan - Nanotechnology Reviews, 2014 - degruyter.com
Self-assembling polysaccharide nanostructures have moved to the forefront of many fields
due to their wide range of functional properties and unique advantages, including …

pH-responsive nanoparticles shelled with chitosan for oral delivery of insulin: from mechanism to therapeutic applications

HW Sung, K Sonaje, ZX Liao, LW Hsu… - Accounts of Chemical …, 2012 - ACS Publications
Despite advances in drug-delivery technologies, successful oral administration of protein
drugs remains an elusive challenge. When protein drugs are administered orally, they can …