Understanding the atomic interaction mechanism between chitosan and insulin at different
pH levels is essential in the design of chitosan-based drug-delivery systems. In the present …

Nano-delivery systems play an important role in the development of nutritional supplements
due to their efficient encapsulation and delivery properties for nutrients. Herein, we prepared …

Therapeutic proteins are labile macromolecules that are prone to degradation during
production, freeze-drying and storage. Recent studies showed that nanoparticles can …

Dextran-covered PLA nanoparticles have been formulated by two strategies. On one hand,
dextran-g-PLA copolymers have been synthesized by click-chemistry between azide …

The ability of lipidic self-assembly systems to solubilize hydrophobic drugs allows for the
enhancement of the delivery of poorly water-soluble drugs. Hydrophobic molecules are …

Delivering therapeutic compound to the target site is a major problem in treatment of many
diseases. A conventional application of drugs is characterized by limited effectiveness, poor …

The insulin loaded nanoparticles composed of poly (lactic-co-glycolic acid)(PLGA) and
hydroxypropyl methylcellulose phthalate (HP55) were prepared via the emulsions solvent …

Biocompatible nanoparticles as drug carriers can improve the therapeutic efficiency of
hydrophobic drugs. However, the synthesis of biocompatible and biodegradable polymeric …

Chitosan–caseinate nanoparticles were synthesized by polyelectrolyte complex (PEC)
formation. Caseinate is an anionic micellar nanocolloid in aqueous solutions, which …

The goal of this work was to design a new nanocarrier composed of the glycosaminoglycan
hyaluronan and the polysaccharide chitosan, intended for the transmucosal delivery of …